MRTFB - Mrtfb myocardin related transcription factor B Gene

Also Known as Mkl2; RGD1560833

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 100362470

Summary

Predicted to enable DNA-binding transcription factor activity; actin binding activity; and transcription coactivator activity. Predicted to be involved in positive regulation of pri-miRNA transcription by RNA polymerase II and positive regulation of striated muscle tissue development. Predicted to act upstream of or within several processes, including animal organ development; generation of neurons; and smooth muscle cell differentiation. Predicted to be located in cytoplasm. Orthologous to human MRTFB (myocardin related transcription factor B). [provided by Alliance of Genome Resources, Apr 2022]

MRTFB Products (6)

mRNA Protein Name
XM_039087008.1 XP_038942936.1 myocardin-related transcription factor B isoform X1
XM_039087009.1 XP_038942937.1 myocardin-related transcription factor B isoform X1
XM_039087007.1 XP_038942935.1 myocardin-related transcription factor B isoform X1
XM_039087010.1 XP_038942938.1 myocardin-related transcription factor B isoform X2
XM_039087012.1 XP_038942940.1 myocardin-related transcription factor B isoform X4
XM_039087011.1 XP_038942939.1 myocardin-related transcription factor B isoform X3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of modification of postsynaptic structure IDA
IDA: Inferred from direct assay
29335431 RGD
involved in regulation of modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
29335431 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29335431 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
29335431 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
29335431 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
29335431 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myocardin-related transcription factor B

  • MKL/myocardin-like 2

  • MKL/myocardin-like protein 2

  • MKL/myocardin-like protein 2-like

  • MKL1/myocardin like 2

  • myocardin like 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08694 MRTFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MRTFB NCBI NCBI:57496