Rpl5 - ribosomal protein L5 Gene

Also Known as Ska23; Skax23; U21RNA; Ska

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100503670

Summary

Predicted to enable RNA binding activity; ubiquitin Ligase inhibitor activity; and ubiquitin protein Ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including positive regulation of aminoacyl-tRNA Ligase activity; regulation of cellular protein metabolic process; and ribosome biogenesis. Located in synapse. Is expressed in several structures, including central nervous system; gonad; intestine; sensory organ; and spleen. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 6; T-cell acute lymphoblastic leukemia; and glioblastoma. Orthologous to human RPL5 (ribosomal protein L5). [provided by Alliance of Genome Resources, Apr 2022]

Rpl5 Products (1)

mRNA Protein Name
NM_016980.2 NP_058676.1 60S ribosomal protein L5

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16648475 MGI
enables structural constituent of ribosome IDA
IDA: Inferred from direct assay
36517592 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
36517592 MGI
part of cytosolic large ribosomal subunit IDA
IDA: Inferred from direct assay
36517592 MGI
part of cytosolic large ribosomal subunit IPI
IPI: Inferred from physical interaction
36517592 MGI
is active in synapse EXP
EXP: Inferred from Experiment
16635246 MGI
is active in synapse IDA
IDA: Inferred from direct assay
16635246 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

60S ribosomal protein L5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12201 RPL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rpl5 NCBI NCBI:6125