SCN8A - sodium voltage-gated channel alpha subunit 8 Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100522189

About SCN8A

Primary_assembly 5: 16,977,700-17,169,543 forward strand.Sscrofa11.1:CM000816.5

This gene has 3 transcripts (splice variants), 276 orthologues and 27 paralogues. Broad expression in mixtures (RPKM 1.3), liver (RPKM 1.1) and 6 other tissues.

SCN8A Products (5)

mRNA Protein Name
XM_021091664.1 XP_020947323.1 sodium channel protein type 8 subunit alpha isoform X1
XM_003481581.4 XP_003481629.2 sodium channel protein type 8 subunit alpha isoform X3
XM_021091666.1 XP_020947325.1 sodium channel protein type 8 subunit alpha isoform X2
XM_021091665.1 XP_020947324.1 sodium channel protein type 8 subunit alpha isoform X1
XM_021091667.1 XP_020947326.1 sodium channel protein type 8 subunit alpha isoform X4

SCN8A Protein Structure

Ion_trans

Ion_trans: pfam00520 (130 - 420)

Na_trans_cytopl

Na_trans_cytopl: pfam11933 (545 - 712)

Ion_trans

Ion_trans: pfam00520 (762 - 975)

Na_trans_assoc

Na_trans_assoc: pfam06512 (1001 - 1202)

Ion_trans

Ion_trans: pfam00520 (1207 - 1483)

Na_channel_gate

Na_channel_gate: cd13433 (1475 - 1527)

Ion_trans

Ion_trans: pfam00520 (1532 - 1786)

GPHH

GPHH: cl25190 (1798 - 1845)

IQ

IQ: smart00015 (1904 - 1925)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 1991 a.a.
Protein Preferred Names Protein Names

sodium channel protein type 8 subunit alpha

  • sodium channel, voltage gated, type VIII, alpha subunit

  • voltage-gated sodium channel alpha subunit Nav1.6

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-147423 Zandatrigine Inhibitor 99.28% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148792 Relutrigine Inhibitor 99.33% Unkown
HY-RS12545 SCN8A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12546 Scn8a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12547 Scn8a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SCN8A NCBI NCBI:6334