2. Gene
  3. SNUPN - snurportin 1 Gene

SNUPN - snurportin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as KPNBL; RNUT1; Snurportin1

Gene ID: 10073 | Gene type: protein coding

About SNUPN

Cytogenetic location: 15q24.2 Genomic coordinates (GRCh38): 15:75,598,086-75,626,461 (from NCBI)

This gene has 11 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in testis (RPKM 12.3), ovary (RPKM 8.3) and 25 other tissues.

Summary

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

SNUPN Products(3)

mRNA Protein Name
NM_001042581.2 NP_001036046.1 snurportin-1
NM_001042588.2 NP_001036053.1 snurportin-1
NM_005701.4 NP_005692.1 snurportin-1

SNUPN Protein Structure

Snurportin1

Snurportin1: Snurportin1 (25 - 64)

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  • 360 a.a.
Protein Preferred Names Protein Names

snurportin-1

RNA U transporter 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13519 SNUPN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SNUPN VGNC VGNC:35088
Felis catus SNUPN VGNC VGNC:104721
Rattus norvegicus SNUPN RGD RGD:1303191
Mus musculus SNUPN MGD MGI:1913319
Canis familiaris SNUPN VGNC VGNC:46618
Macaca mulatta SNUPN VGNC VGNC:99242