TSHZ1 - teashirt zinc finger homeobox 1 Gene

Also Known as CAA; TSH1; NY-CO-33; SDCCAG33

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 10194

About TSHZ1

Cytogenetic location: 18q22.3 Genomic coordinates (GRCh38): 18:75,210,797-75,289,944 (from NCBI)

This gene has 5 transcripts (splice variants), 267 orthologues, 2 paralogues and is associated with 3 phenotypes. Ubiquitous expression in ovary (RPKM 18.5), placenta (RPKM 15.6) and 24 other tissues.

Summary

This gene encodes a colon Cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]

TSHZ1 Products (2)

mRNA	Protein	Name
NM_001308210.2	NP_001295139.1	teashirt homolog 1 isoform 1
NM_005786.6	NP_005777.3	teashirt homolog 1 isoform 2

TSHZ1 Protein Structure

zf-C2H2_2

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1077 a.a.

Protein Preferred Names	Protein Names
teashirt homolog 1	antigen NY-CO-33

Related Diseases

Diseases	Alias
Aural Atresia, Congenital	CAA Aural Atresia, Congenital, With Hyposmia
External Auditory Canal Aplasia/Hypoplasia	External Auditory Canal Stenosis/Atresia Anomaly Of Osseous Meatus
Vertical Talus, Congenital	Congenital Vertical Talus CVT Congenital Convex Pes Valgus Rocker-Bottom Foot Deformity Vertical Talus Pes Valgus, Congenital Convex Congenital Convex Foot Congenital Rocker-Bottom Foot Rocker Bottom Foot Flatfoot Rocker-Bottom Foot Charcot-Marie-Tooth Disease, Foot Deformity Of
Chromosome 18q Deletion Syndrome	18q- Syndrome Monosomy 18q Deletion Of Long Arm Of Chromosome 18 Chromosome 18q- Syndrome Deletion 18q 18q Deletion Syndrome Distal 18q Deletion Syndrome Chromosome 18 Long Arm Deletion Syndrome Chromosome 18q Monosomy Del Syndrome Chromosome 18 Deletion Syndrome
Valproate Embryopathy	Fetal Valproate Syndrome Fetal Valproic Acid Syndrome Fvs Valproic Acid Embryopathy Fetal Valproate Spectrum Disorder Valproate Embryopathy, Susceptibility To Foetal Valproate Syndrome Foetal Valproic Acid Syndrome Susceptibility To Valproate Embryopathy Valproic Acid Antenatal Infection
Hypertrichosis Universalis Congenita, Ambras Type	Ambras Syndrome Hypertrichosis, Congenital Generalized HTC1 HTC2 Chromosome Xq27.1 Interchromosomal Insertion Syndrome Cgh Hcg Ambras Type Hypertrichosis Universalis Congenita X-Linked Congenital Generalized Hypertrichosis Congenital Generalized Hypertrichosis, Macias-Flores Type Macias Flores-Garcia Cruz-Rivera Syndrome Htc 1 Hypertrichosis Universalis Congenita Ambras Type Hypertrichosis Congenital Generalized X-Linked Macias-Flores Garcia-Cruz Rivera Syndrome Congenital Generalized Hypertrichosis, Ambras Type
Substance-Induced Psychosis
Cleft Soft Palate	Cleft Velum Cleft Velum Palatinum Soft Cleft Palate Soft Palate Perforation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15148	TSHZ1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22884	Tshz1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TSHZ1	VGNC	VGNC:47903
Macaca mulatta	TSHZ1	VGNC	VGNC:78553
Felis catus	TSHZ1	VGNC	VGNC:80541
Mus musculus	TSHZ1	MGD	MGI:1346031
Rattus norvegicus	TSHZ1	RGD	RGD:1311684
Bos taurus	TSHZ1	VGNC	VGNC:56375