2. Gene
  3. SCN8A - sodium voltage-gated channel alpha subunit 8 Gene

SCN8A - sodium voltage-gated channel alpha subunit 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca fascicularis
Gene ID: 102142199 | Gene type: protein coding

About SCN8A

Primary_assembly 11: 50,735,994-50,944,273 forward strand.Macaca_fascicularis_6.0:CM021949.1

This gene has 4 transcripts (splice variants), 276 orthologues and 28 paralogues.

SCN8A Products(10)

mRNA Protein Name
XM_045365279.1 XP_045221214.1 sodium channel protein type 8 subunit alpha isoform X1
XM_015430942.2 XP_015286428.1 sodium channel protein type 8 subunit alpha isoform X1
XM_045365280.1 XP_045221215.1 sodium channel protein type 8 subunit alpha isoform X3
XM_045365277.1 XP_045221212.1 sodium channel protein type 8 subunit alpha isoform X2
XM_045365281.1 XP_045221216.1 sodium channel protein type 8 subunit alpha isoform X4
XM_045365285.1 XP_045221220.1 sodium channel protein type 8 subunit alpha isoform X7
XM_045365283.1 XP_045221218.1 sodium channel protein type 8 subunit alpha isoform X5
XM_045365276.1 XP_045221211.1 sodium channel protein type 8 subunit alpha isoform X1
XM_045365284.1 XP_045221219.1 sodium channel protein type 8 subunit alpha isoform X6
XM_045365278.1 XP_045221213.1 sodium channel protein type 8 subunit alpha isoform X1

SCN8A Protein Structure

Ion_trans

Ion_trans: pfam00520 (130 - 420)

Na_trans_cytopl

Na_trans_cytopl: pfam11933 (545 - 712)

Ion_trans

Ion_trans: pfam00520 (762 - 975)

Na_trans_assoc

Na_trans_assoc: pfam06512 (1001 - 1202)

Ion_trans

Ion_trans: pfam00520 (1207 - 1483)

Na_channel_gate

Na_channel_gate: cd13433 (1475 - 1527)

Ion_trans

Ion_trans: pfam00520 (1532 - 1786)

GPHH

GPHH: cl25190 (1798 - 1845)

IQ

IQ: smart00015 (1904 - 1925)

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  • 1991 a.a.
Protein Preferred Names Protein Names

sodium channel protein type 8 subunit alpha

sodium channel, voltage gated, type VIII, alpha subunit

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-147423 Zandatrigine Inhibitor 99.28% Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148792 Relutrigine Inhibitor 99.33% Unkown
HY-RS12545 SCN8A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12546 Scn8a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12547 Scn8a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SCN8A NCBI NCBI:6334