SCN8A - sodium voltage-gated channel alpha subunit 8 Gene
Species: Macaca fascicularis
Gene Type: protein coding
Gene ID: 102142199
About SCN8A
Primary_assembly 11: 50,735,994-50,944,273 forward strand.Macaca_fascicularis_6.0:CM021949.1
This gene has 4 transcripts (splice variants), 276 orthologues and 28 paralogues.
SCN8A Products (10)
| mRNA | Protein | Name |
|---|---|---|
| XM_045365279.1 | XP_045221214.1 | sodium channel protein type 8 subunit alpha isoform X1 |
| XM_015430942.2 | XP_015286428.1 | sodium channel protein type 8 subunit alpha isoform X1 |
| XM_045365280.1 | XP_045221215.1 | sodium channel protein type 8 subunit alpha isoform X3 |
| XM_045365277.1 | XP_045221212.1 | sodium channel protein type 8 subunit alpha isoform X2 |
| XM_045365281.1 | XP_045221216.1 | sodium channel protein type 8 subunit alpha isoform X4 |
| XM_045365285.1 | XP_045221220.1 | sodium channel protein type 8 subunit alpha isoform X7 |
| XM_045365283.1 | XP_045221218.1 | sodium channel protein type 8 subunit alpha isoform X5 |
| XM_045365276.1 | XP_045221211.1 | sodium channel protein type 8 subunit alpha isoform X1 |
| XM_045365284.1 | XP_045221219.1 | sodium channel protein type 8 subunit alpha isoform X6 |
| XM_045365278.1 | XP_045221213.1 | sodium channel protein type 8 subunit alpha isoform X1 |
SCN8A Protein Structure
Ion_trans
Ion_trans: pfam00520 (130 - 420)
Na_trans_cytopl
Na_trans_cytopl: pfam11933 (545 - 712)
Ion_trans
Ion_trans: pfam00520 (762 - 975)
Na_trans_assoc
Na_trans_assoc: pfam06512 (1001 - 1202)
Ion_trans
Ion_trans: pfam00520 (1207 - 1483)
Na_channel_gate
Na_channel_gate: cd13433 (1475 - 1527)
Ion_trans
Ion_trans: pfam00520 (1532 - 1786)
GPHH
GPHH: cl25190 (1798 - 1845)
IQ
IQ: smart00015 (1904 - 1925)
- 0
- 400
- 800
- 1200
- 1600
- 1991 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sodium channel protein type 8 subunit alpha |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-147423 | Zandatrigine | Inhibitor | 99.28% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-148792 | Relutrigine | Inhibitor | 99.33% | Unkown |
| HY-RS12545 | SCN8A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12546 | Scn8a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS12547 | Scn8a Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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