Gpat4 - glycerol-3-phosphate acyltransferase 4 Gene

Also Known as Agpat6; Tsarg7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 102247

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Involved in triglyceride biosynthetic process. Acts upstream of or within several processes, including acylglycerol metabolic process; glandular epithelial cell maturation; and lactation. Located in endoplasmic reticulum. Is expressed in several structures, including adipose tissue; brain; genitourinary system; liver; and mammary gland. Orthologous to human GPAT4 (glycerol-3-phosphate Acyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

Gpat4 Products (1)

mRNA Protein Name
NM_018743.4 NP_061213.2 glycerol-3-phosphate acyltransferase 6 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glycerol-3-phosphate O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
18238778 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
27806294 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within diacylglycerol metabolic process IMP
IMP: Inferred from mutant phenotype
16436371 MGI
acts upstream of or within fatty acid metabolic process IMP
IMP: Inferred from mutant phenotype
16436371 MGI
acts upstream of or within glandular epithelial cell maturation IMP
IMP: Inferred from mutant phenotype
16449762 MGI
acts upstream of or within lactation IMP
IMP: Inferred from mutant phenotype
16449762 MGI
involved in lactation IMP
IMP: Inferred from mutant phenotype
16449762 MGI
involved in lipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
16449762 MGI
acts upstream of or within mammary gland development IMP
IMP: Inferred from mutant phenotype
16449762 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
16436371 MGI
involved in triglyceride biosynthetic process IMP
IMP: Inferred from mutant phenotype
16436371 MGI
acts upstream of or within triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
16436371 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
16449762 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate acyltransferase 6

  • 1-AGP acyltransferase 6

  • 1-AGPAT 6

  • 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)

  • LPAAT-zeta

  • acyl-CoA:glycerol-3-phosphate acyltransferase 4

  • lysophosphatidic acid acyltransferase zeta

  • putative lysophospha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05618 GPAT4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpat4 NCBI NCBI:137964