Gpat4 - glycerol-3-phosphate acyltransferase 4 Gene

Mus musculus

Also known as Agpat6; Tsarg7

Gene ID: 102247 | Gene type: protein coding

About Gpat4

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Involved in triglyceride biosynthetic process. Acts upstream of or within several processes, including acylglycerol metabolic process; glandular epithelial cell maturation; and lactation. Located in endoplasmic reticulum. Is expressed in several structures, including adipose tissue; brain; genitourinary system; liver; and mammary gland. Orthologous to human GPAT4 (glycerol-3-phosphate Acyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

Gpat4 Products(1)

mRNA	Protein	Name
NM_018743.4	NP_061213.2	glycerol-3-phosphate acyltransferase 6 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables glycerol-3-phosphate O-acyltransferase activity	IMP IMP: Inferred from mutant phenotype	18238778	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	27806294	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within diacylglycerol metabolic process	IMP IMP: Inferred from mutant phenotype	16436371	MGI
acts upstream of or within fatty acid metabolic process	IMP IMP: Inferred from mutant phenotype	16436371	MGI
acts upstream of or within glandular epithelial cell maturation	IMP IMP: Inferred from mutant phenotype	16449762	MGI
acts upstream of or within lactation	IMP IMP: Inferred from mutant phenotype	16449762	MGI
involved in lactation	IMP IMP: Inferred from mutant phenotype	16449762	MGI
involved in lipid biosynthetic process	IMP IMP: Inferred from mutant phenotype	16449762	MGI
acts upstream of or within mammary gland development	IMP IMP: Inferred from mutant phenotype	16449762	MGI
acts upstream of or within regulation of multicellular organism growth	IMP IMP: Inferred from mutant phenotype	16436371	MGI
involved in triglyceride biosynthetic process	IMP IMP: Inferred from mutant phenotype	16436371	MGI
acts upstream of or within triglyceride metabolic process	IMP IMP: Inferred from mutant phenotype	16436371	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	16449762	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glycerol-3-phosphate acyltransferase 6

1-AGP acyltransferase 6	1-AGPAT 6
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)	LPAAT-zeta
acyl-CoA:glycerol-3-phosphate acyltransferase 4	lysophosphatidic acid acyltransferase zeta
putative lysophospha

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05618	GPAT4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpat4	NCBI	NCBI:137964

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