APELA - Apela apelin receptor early endogenous ligand Gene

Rattus norvegicus

Also known as ELA; Tdl

Gene ID: 103693925 | Gene type: protein coding

About APELA

Summary

Predicted to enable apelin receptor binding activity and hormone activity. Predicted to be involved in several processes, including apelin receptor signaling pathway; circulatory system development; and positive regulation of G protein-coupled receptor internalization. Predicted to act upstream of or within SMAD protein signal transduction. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

APELA Products(1)

mRNA	Protein	Name
NM_001399424.1	NP_001386353.1	apelin receptor early endogenous ligand precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables apelin receptor binding	IDA IDA: Inferred from direct assay	26611206	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in apelin receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	26611206	RGD
involved in positive regulation of ERK1 and ERK2 cascade	IMP IMP: Inferred from mutant phenotype	26611206	RGD
involved in positive regulation of heart contraction	IMP IMP: Inferred from mutant phenotype	26611206	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

apelin receptor early endogenous ligand

Protein Elabela

Protein Toddler

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00814	APELA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	APELA	NCBI	NCBI:100506013

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