2. Gene
  3. Hoxb2 - homeobox B2 Gene

Hoxb2 - homeobox B2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hox-2.8; Hoxbes2

Gene ID: 103889 | Gene type: protein coding

About Hoxb2

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including central nervous system development; embryonic skeletal system morphogenesis; and regionalization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; future hindbrain; lung; metanephros; and nervous system. Orthologous to human HOXB2 (homeobox B2). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb2 Products(1)

mRNA Protein Name
NM_134032.2 NP_598793.2 homeobox protein Hox-B2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
9012503 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
9012503 MGI
acts upstream of or within dorsal/ventral pattern formation IGI
IGI: Inferred from genetic interaction
10230789 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
10885747 MGI
acts upstream of or within facial nerve structural organization IMP
IMP: Inferred from mutant phenotype
9012503 MGI
acts upstream of or within morphogenesis of an epithelial sheet IGI
IGI: Inferred from genetic interaction
11518511 MGI
acts upstream of or within neural nucleus development IMP
IMP: Inferred from mutant phenotype
9012503 MGI
acts upstream of or within rhombomere 3 development IGI
IGI: Inferred from genetic interaction
10230789 MGI
acts upstream of or within rhombomere 4 development IGI
IGI: Inferred from genetic interaction
10230789 MGI
acts upstream of or within skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
9012503 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
9012503 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B2

homeo box B2

homeobox protein Hox-2.8

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06306 HOXB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb2 NCBI NCBI:3212