ADARB2 - adenosine deaminase RNA specific B2 (inactive) Gene

Also Known as RED2; ADAR3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 105

About ADARB2

Cytogenetic location: 10p15.3 Genomic coordinates (GRCh38): 10:1,177,313-1,737,525 (from NCBI)

This gene has 7 transcripts (splice variants), 279 orthologues and 14 paralogues. Biased expression in brain (RPKM 4.7), salivary gland (RPKM 0.5) and 3 other tissues.

Summary

This gene encodes a member of the double-stranded RNA Adenosine Deaminase family of RNA-editing Enzymes and may play a regulatory role in RNA editing. [provided by RefSeq, Jul 2008]

ADARB2 Products (1)

mRNA Protein Name
NM_018702.4 NP_061172.1 double-stranded RNA-specific editase B2

ADARB2 Protein Structure

dsrm

dsrm: Double-stranded RNA binding motif (126 - 187)

dsrm

dsrm: Double-stranded RNA binding motif (287 - 339)

A_deamin

A_deamin: Adenosine-deaminase (editase) domain (408 - 731)

  • 0
  • 200
  • 400
  • 600
  • 739 a.a.
Protein Preferred Names Protein Names

double-stranded RNA-specific editase B2

  • RED2 homolog

Related Diseases

Diseases Alias
Childhood Astrocytic Tumor

  • Juvenile Astrocytoma

  • Pediatric Astrocytoma
Dyschromatosis Symmetrica Hereditaria

  • Dyschromatosis Symmetrica Hereditaria 1

  • Reticulate Acropigmentation Of Dohi

  • DSH

  • Dsh1

  • Symmetric Dyschromatosis Of The Extremities

  • Rad

  • Familial Reticulate Acropigmentation Of Dohi

  • Acropigmentation Of Dohi

  • Symmetrical Dyschromatosis Of Extremities
Aicardi-Goutieres Syndrome

  • Aicardi Goutieres Syndrome

  • Cree Encephalitis

  • Aicardi-Goutières Syndrome

  • Encephalopathy With Basal Ganglia Calcification

  • Ags

  • Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

  • Pseudotoxoplasmosis Syndrome

  • Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

  • Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

  • Aicardi-Goutieres Syndrome 1
Spinocerebellar Ataxia 8

  • Spinocerebellar Ataxia Type 8

  • SCA8

  • Ataxia, Spinocerebellar, Type 8
Amyotrophic Lateral Sclerosis 1

  • Amyotrophic Lateral Sclerosis

  • ALS

  • Lou Gehrig Disease

  • Amyotrophic Lateral Sclerosis Type 1

  • Charcot Disease

  • ALS1

  • Amyotrophic Lateral Sclerosis, Susceptibility To

  • Fals

  • Lou Gehrig'S Disease

  • Mnd

  • Motor Neuron Disease

  • Familial Amyotrophic Lateral Sclerosis

  • Amyotrophic Lateral Sclerosis 1, Familial

  • Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

  • Motor Neuron Disease, Bulbar

  • Motor Neurone Disease

  • Amyotrophic Lateral Sclerosis With Dementia

  • Dementia With Amyotrophic Lateral Sclerosis

  • Motor Neuron Disease, Amyotrophic Lateral Sclerosis

  • Sclerosis, Lateral, Amyotrophic

  • Sclerosis, Lateral, Amyotrophic, Type 1

  • Amyotrophic Sclerosis

  • Als - [Amyotrophic Lateral Sclerosis]

  • Wasting Palsy

  • Amyotrophic Paralysis

  • Amyotrophy Lateral Sclerosis

  • Wasting Paralysis

  • Spinal Progressive Amyotrophy

  • Progressive Atrophic Paralysis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00319 ADARB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ADARB2 MGD MGI:2151118
Macaca mulatta ADARB2 VGNC VGNC:100290
Felis catus ADARB2 VGNC VGNC:83490
Rattus norvegicus ADARB2 RGD RGD:621519