Arrdc3 - arrestin domain containing 3 Gene

Also Known as mKIAA1376

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105171

Summary

Predicted to enable beta-3 Adrenergic Receptor binding activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including fat pad development; negative regulation of adenylate cyclase-activating Adrenergic Receptor signaling pathway; and negative regulation of locomotion involved in locomotory behavior. Predicted to be located in lysosome and membrane. Predicted to be active in endosome and plasma membrane. Is expressed in central nervous system; liver; lung; olfactory epithelium; and retina nuclear layer. Orthologous to human ARRDC3 (Arrestin domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Arrdc3 Products (1)

mRNA Protein Name
NM_001042591.2 NP_001036056.1 arrestin domain-containing protein 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within fat pad development IMP
IMP: Inferred from mutant phenotype
21982743 MGI
acts upstream of heat generation IMP
IMP: Inferred from mutant phenotype
21982743 MGI
acts upstream of or within negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
21982743 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
21982743 MGI
acts upstream of or within negative regulation of heat generation IMP
IMP: Inferred from mutant phenotype
21982743 MGI
acts upstream of or within negative regulation of locomotion involved in locomotory behavior IMP
IMP: Inferred from mutant phenotype
21982743 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
23236378 MGI
acts upstream of or within temperature homeostasis IMP
IMP: Inferred from mutant phenotype
21982743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arrestin domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01032 ARRDC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arrdc3 NCBI NCBI:57561