RRH - retinal pigment epithelium-derived rhodopsin homolog Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10692

About RRH

Cytogenetic location: 4q25 Genomic coordinates (GRCh38): 4:109,827,972-109,844,942 (from NCBI)

This gene has 3 transcripts (splice variants), 200 orthologues and 9 paralogues. Low expression observed in reference dataset.

Summary

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled receptor. [provided by RefSeq, Jul 2008]

RRH Products (1)

mRNA Protein Name
NM_006583.5 NP_006574.1 visual pigment-like receptor peropsin

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RRH Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (43 - 294)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
Protein Preferred Names Protein Names

visual pigment-like receptor peropsin

  • peropsin

RRH Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RRH O14718 NSG2 Homo sapiens Q9Y328
Validated Y2H
32296183
Intra
RRH O14718 NSG2 Homo sapiens Q9Y328
Y2H Prey Pooling
32296183
Intra
RRH O14718 NSG2 Homo sapiens Q9Y328
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Trombiculiasis
Subglottis Benign Neoplasm

  • Subglottic Tumor
Ulcerative Stomatitis

  • Stomatitis Ulcerative

  • Aphthous Stomatitis

  • Minor Oral Aphthous Ulceration
Noma

  • Cancrum Oris

  • Gangrenous Stomatitis

  • Oro-Facial Gangrene

  • Noma Neonatorum

  • Oral Gangrene

  • Oro-Facial Noma

  • Stomatitis Gangrenosa

  • Stomatonecrosis

  • Gangrene Stomatitis
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12284 RRH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18022 Rrh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24495 Rrh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RRH VGNC VGNC:76940
Rattus norvegicus RRH RGD RGD:1308948
Felis catus RRH VGNC VGNC:64774
Canis familiaris RRH VGNC VGNC:45759
Bos taurus RRH VGNC VGNC:34163
Mus musculus RRH MGD MGI:1097709
Others RRH NCBI