Drgx - dorsal root ganglia homeobox Gene

Mus musculus

Also known as Drg11; Prrxl1

Gene ID: 107751 | Gene type: protein coding

About Drgx

Summary

Enables DNA binding activity. Acts upstream of or within several processes, including detection of temperature stimulus; nervous system development; and sensory perception of mechanical stimulus. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; and trunk somite. Orthologous to human DRGX (dorsal root ganglia homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Drgx Products(2)

mRNA	Protein	Name
NM_001001796.4	NP_001001796.1	dorsal root ganglia homeobox protein isoform 2
NM_001347590.1	NP_001334519.1	dorsal root ganglia homeobox protein isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	14985445	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within axon guidance	IMP IMP: Inferred from mutant phenotype	12917357	MGI
acts upstream of or within axonogenesis	IMP IMP: Inferred from mutant phenotype	11498051	MGI
acts upstream of or within detection of chemical stimulus	IMP IMP: Inferred from mutant phenotype	11498051	MGI
acts upstream of or within detection of temperature stimulus	IMP IMP: Inferred from mutant phenotype	11498051	MGI
acts upstream of or within dorsal spinal cord development	IMP IMP: Inferred from mutant phenotype	16978876	MGI
acts upstream of or within nervous system development	IMP IMP: Inferred from mutant phenotype	11498051	MGI
acts upstream of or within neuron differentiation	IMP IMP: Inferred from mutant phenotype	16978876	MGI
acts upstream of or within neuron migration	IMP IMP: Inferred from mutant phenotype	15229182	MGI
acts upstream of or within sensory perception of mechanical stimulus	IMP IMP: Inferred from mutant phenotype	11498051	MGI
acts upstream of or within trigeminal nerve development	IMP IMP: Inferred from mutant phenotype	12917357	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dorsal root ganglia homeobox protein

dorsal root ganglion 11	homeobox protein DRG11
paired homeodomain protein DRG11	paired related homeobox protein-like 1
paired related homeobox protein-like 1b

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04011	DRGX Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Drgx	NCBI	NCBI:644168

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