Drgx - dorsal root ganglia homeobox Gene

Also Known as Drg11; Prrxl1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107751

Summary

Enables DNA binding activity. Acts upstream of or within several processes, including detection of temperature stimulus; nervous system development; and sensory perception of mechanical stimulus. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; and trunk somite. Orthologous to human DRGX (dorsal root ganglia homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Drgx Products (2)

mRNA Protein Name
NM_001001796.4 NP_001001796.1 dorsal root ganglia homeobox protein isoform 2
NM_001347590.1 NP_001334519.1 dorsal root ganglia homeobox protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
14985445 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
12917357 MGI
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
11498051 MGI
acts upstream of or within detection of chemical stimulus IMP
IMP: Inferred from mutant phenotype
11498051 MGI
acts upstream of or within detection of temperature stimulus IMP
IMP: Inferred from mutant phenotype
11498051 MGI
acts upstream of or within dorsal spinal cord development IMP
IMP: Inferred from mutant phenotype
16978876 MGI
acts upstream of or within nervous system development IMP
IMP: Inferred from mutant phenotype
11498051 MGI
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
16978876 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
15229182 MGI
acts upstream of or within sensory perception of mechanical stimulus IMP
IMP: Inferred from mutant phenotype
11498051 MGI
acts upstream of or within trigeminal nerve development IMP
IMP: Inferred from mutant phenotype
12917357 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dorsal root ganglia homeobox protein

  • dorsal root ganglion 11

  • homeobox protein DRG11

  • paired homeodomain protein DRG11

  • paired related homeobox protein-like 1

  • paired related homeobox protein-like 1b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04011 DRGX Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Drgx NCBI NCBI:644168