Lin7a - lin-7 homolog A, crumbs cell polarity complex component Gene

Also Known as Veli; Veli1; LIN-7A; MALS-1; TIP-33

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108030

Summary

Predicted to enable L27 domain binding activity and PDZ domain binding activity. Acts upstream of or within inner ear development; neurotransmitter secretion; and synaptic vesicle transport. Located in basolateral plasma membrane. Is expressed in glans of male genital tubercle; lung; nervous system; paraxial mesenchyme; and sensory organ. Orthologous to human LIN7A (lin-7 homolog A, crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Apr 2022]

Lin7a Products (3)

mRNA Protein Name
NM_001033223.3 NP_001028395.1 protein lin-7 homolog A isoform 2
NM_001039354.2 NP_001034443.1 protein lin-7 homolog A isoform 1
NM_001284329.2 NP_001271258.1 protein lin-7 homolog A isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18054859 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inner ear development IDA
IDA: Inferred from direct assay
21795542 MGI
acts upstream of or within neurotransmitter secretion IGI
IGI: Inferred from genetic interaction
16186258 MGI
acts upstream of or within synaptic vesicle transport IMP
IMP: Inferred from mutant phenotype
14622577 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
12351654 MGI
located in membrane IDA
IDA: Inferred from direct assay
18054859 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein lin-7 homolog A

  • lin 7 homolog a

  • lin-7 homolog A

  • mammalian LIN-7 1

  • mammalian lin-seven protein 1

  • vertebrate homolog of C. elegans Lin-7 type 1

  • vertebrate lin-7 homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07676 LIN7A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lin7a NCBI NCBI:8825