IFI44L - interferon induced protein 44 like Gene

Homo sapiens

Also known as GS3686; TLDC5B; C1orf29

Gene ID: 10964 | Gene type: protein coding

About IFI44L

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,620,448-78,646,145 (from NCBI)

This gene has 18 transcripts (splice variants), 1015 orthologues and 1 paralogue. Broad expression in spleen (RPKM 16.8), bone marrow (RPKM 13.1) and 23 other tissues.

Summary

Predicted to enable GTP binding activity. Involved in defense response to virus. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

IFI44L Products(6)

mRNA	Protein	Name
NM_001375646.1	NP_001362575.1	interferon-induced protein 44-like isoform 1
NM_001375647.1	NP_001362576.1	interferon-induced protein 44-like isoform 2
NM_001375648.1	NP_001362577.1	interferon-induced protein 44-like isoform 2
NM_001375649.1	NP_001362578.1	interferon-induced protein 44-like isoform 2
NM_001375650.1	NP_001362579.1	interferon-induced protein 44-like isoform 2
NM_006820.4	NP_006811.2	interferon-induced protein 44-like isoform 1

Protein Preferred Names

Protein Names

interferon-induced protein 44-like

Related Diseases

Diseases

Alias

Multisystem Inflammatory Syndrome In Children

Mis-C	Multisystem Inflammatory Disorder In Children And Adolescents
Paediatric Inflammatory Multisystemic Syndrome	Mic

Immunodeficiency 38 With Basal Ganglia Calcification

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Isg15 Deficiency	IMD38
Immunodeficiency 38, Mycobacteriosis, Autosomal Recessive	Immunodeficiency 38
Isg15 Deficiency, Autosomal Recessive	Immunodeficiency 38, With Basal Ganglia Calcification
Autosomal Recessive Isg15 Deficiency	Msmd Due To Complete Isg15 Deficiency
Immunodeficiency, Type 38

Potocki-Shaffer Syndrome

Proximal 11p Deletion Syndrome	Chromosome 11p11.2 Deletion Syndrome
Pss	11p11.2 Deletion
P11pds	Defect11 Syndrome
Deletion Of Chromosome 11p11.2	POSHS

Lymph Node Tuberculosis

King'S Evil	Scrofula
Tuberculous Adenitis	Tuberculous Lymphadenopathy
Tuberculosis, Lymph Node

Childhood Type Dermatomyositis

Juvenile Dermatomyositis	Juvenile Dm
Childhood Dermatomyositis	Amyopathic Dermatomyositis
Adm	Dermatomyositis Sine Myositis
Dermatomyositis, Childhood Type

Aicardi-Goutieres Syndrome

Aicardi Goutieres Syndrome	Cree Encephalitis
Aicardi-Goutières Syndrome	Encephalopathy With Basal Ganglia Calcification
Ags	Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid
Pseudotoxoplasmosis Syndrome	Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis
Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis	Aicardi-Goutieres Syndrome 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06557	IFI44L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	IFI44L	VGNC	VGNC:30046
Rattus norvegicus	IFI44L	RGD	RGD:1595861
Macaca mulatta	IFI44L	VGNC	VGNC:73407
Felis catus	IFI44L	VGNC	VGNC:62874
Mus musculus	IFI44L	MGD	MGI:95975
Canis familiaris	IFI44L	VGNC	VGNC:41874

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