Hyal3 - hyaluronoglucosaminidase 3 Gene

Also Known as Hyl3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109685

Summary

Enables hyalurononglucosaminidase activity. Involved in several processes, including hyaluronan catabolic process; negative regulation of ovarian follicle development; and ovarian follicle atresia. Located in cytoplasmic vesicle; endoplasmic reticulum; and sperm midpiece. Is expressed in several structures, including cardiovascular system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human HYAL3 (hyaluronidase 3). [provided by Alliance of Genome Resources, Apr 2022]

Hyal3 Products (1)

mRNA Protein Name
NM_178020.3 NP_821139.2 hyaluronidase-3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables hyalurononglucosaminidase activity IDA
IDA: Inferred from direct assay
18234732 MGI
enables hyalurononglucosaminidase activity IDA
IDA: Inferred from direct assay
20586096 MGI
NOT enables virus receptor activity IDA
IDA: Inferred from direct assay
11296287 MGI
Biological Process GO Annotation Evidence References Source
involved in hyaluronan catabolic process IDA
IDA: Inferred from direct assay
20586096 MGI
involved in negative regulation of ovarian follicle development IDA
IDA: Inferred from direct assay
18653706 MGI
involved in ovarian follicle atresia IDA
IDA: Inferred from direct assay
18653706 MGI
involved in penetration of zona pellucida IMP
IMP: Inferred from mutant phenotype
20586096 MGI
involved in positive regulation of acrosomal vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
20586096 MGI
involved in response to virus IDA
IDA: Inferred from direct assay
11296287 MGI
Cellular Component GO Annotation Evidence References Source
located in acrosomal membrane IDA
IDA: Inferred from direct assay
20586096 MGI
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
20586096 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
18234732 MGI
located in early endosome IDA
IDA: Inferred from direct assay
18234732 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
18234732 MGI
located in sperm midpiece IDA
IDA: Inferred from direct assay
20586096 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hyaluronidase-3

  • hyal-3

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991212 Berahyaluronidase alfa Degrader 99.01% Unkown

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06497 HYAL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13628 SPAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hyal3 NCBI NCBI:8372