Cela1 - chymotrypsin-like elastase family, member 1 Gene

Mus musculus

Also known as Ela1; Ela-1; PC-TsF; 1810009A17Rik; 1810062B19Rik

Gene ID: 109901 | Gene type: protein coding

About Cela1

Summary

Predicted to enable serine-type endopeptidase activity. Acts upstream of or within several processes, including elastin catabolic process; pancreas development; and regulation of transcription by RNA polymerase II. Located in collagen-containing extracellular matrix. Is expressed in alveolus epithelium; lung; pancreas; pancreas tip epithelium; and right lung accessory lobe. Orthologous to human CELA1 (chymotrypsin like Elastase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cela1 Products(1)

mRNA	Protein	Name
NM_033612.2	NP_291090.2	chymotrypsin-like elastase family member 1 precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables serine-type endopeptidase activity	IDA IDA: Inferred from direct assay	35749514	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within Wnt signaling pathway	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within digestive system development	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within elastin catabolic process	IMP IMP: Inferred from mutant phenotype	24793170	MGI
acts upstream of or within exocrine pancreas development	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within inflammatory response	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within multicellular organism growth	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within pancreas morphogenesis	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within positive regulation of angiogenesis	IDA IDA: Inferred from direct assay	24793170	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within post-embryonic development	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within regulation of cell differentiation	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	17222338	MGI
acts upstream of or within tissue remodeling	IMP IMP: Inferred from mutant phenotype	24793170	MGI
acts upstream of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	17222338	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

chymotrypsin-like elastase family member 1

elastase 1, pancreatic

elastase-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02455	CELA1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cela1	NCBI	NCBI:1990

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