Cela1 - chymotrypsin-like elastase family, member 1 Gene

Also Known as Ela1; Ela-1; PC-TsF; 1810009A17Rik; 1810062B19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109901

Summary

Predicted to enable serine-type endopeptidase activity. Acts upstream of or within several processes, including elastin catabolic process; pancreas development; and regulation of transcription by RNA polymerase II. Located in collagen-containing extracellular matrix. Is expressed in alveolus epithelium; lung; pancreas; pancreas tip epithelium; and right lung accessory lobe. Orthologous to human CELA1 (chymotrypsin like Elastase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cela1 Products (1)

mRNA Protein Name
NM_033612.2 NP_291090.2 chymotrypsin-like elastase family member 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
35749514 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within digestive system development IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within elastin catabolic process IMP
IMP: Inferred from mutant phenotype
24793170 MGI
acts upstream of or within exocrine pancreas development IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within pancreas morphogenesis IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within positive regulation of angiogenesis IDA
IDA: Inferred from direct assay
24793170 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within regulation of cell differentiation IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17222338 MGI
acts upstream of or within tissue remodeling IMP
IMP: Inferred from mutant phenotype
24793170 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17222338 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chymotrypsin-like elastase family member 1

  • elastase 1, pancreatic

  • elastase-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02455 CELA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cela1 NCBI NCBI:1990