CELA1 - chymotrypsin like elastase 1 Gene

Also Known as ELA1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1990

About CELA1

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:51,328,442-51,346,679 (from NCBI)

This gene has 1 transcript (splice variant), 325 orthologues and 6 paralogues. Low expression observed in reference dataset.

Summary

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six Elastase genes which encode the structurally similar proteins Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike Other elastases, pancreatic Elastase 1 is not expressed in the pancreas. To date, Elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human Elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like Elastase family, member 3B. [provided by RefSeq, May 2009]

CELA1 Products (1)

mRNA Protein Name
NM_001971.6 NP_001962.3 chymotrypsin-like elastase family member 1

CELA1 Protein Structure

Trypsin

Trypsin: Trypsin (19 - 251)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

chymotrypsin-like elastase family member 1

  • chymotrypsin like elastase family member 1

Related Diseases

Diseases Alias
Pancreatic Steatorrhea

  • Pancreatic Steatorrhoea

  • Decreased Tolerance Of Pancreas

  • Pancreatic Disturbance Of Fat Absorption
Pancreatic Acinar Cell Adenocarcinoma

  • Pancreatic Acinar Cell Carcinoma

  • Acinar Cell Adenocarcinoma Of The Pancreas
Autoimmune Pancreatitis

  • Lymphoplasmocytic Sclerosing Pancreatitis

  • Aip
Exocrine Pancreatic Insufficiency
Biliary Dyskinesia

  • Sphincter Of Oddi Dysfunction
Acute Necrotizing Pancreatitis

  • Pancreatitis, Acute Necrotizing
Celiac Disease 1

  • Celiac Disease

  • Coeliac Disease

  • Celiac Sprue

  • Celiac Disease, Susceptibility To

  • Gluten-Sensitive Enteropathy

  • Nontropical Sprue

  • Sprue

  • CELIAC1

  • Celiac Disease, Susceptibility To, 1

  • Celiac Sprue 1

  • Celiac Sprue, Susceptibility To, 1

  • Gluten-Sensitive Enteropathy 1

  • Gluten-Sensitive Enteropathy, Susceptibility To, 1

  • Idiopathic Steatorrhea

  • Cœliac Disease

  • Gluten Intolerance

  • Gluten-Induced Enteropathy

  • Gluten Enteropathy

  • Celiac Disease, Susceptibility To, Type 1

  • Childhood Celiac Disease

  • Coeliac Rickets

  • Gee Disease

  • Gee-Herter Disease

  • Heubner-Herter Disease

  • Idiopathic Steatorrhoea

  • Thaysen'S Disease

  • Herter Gee Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02455 CELA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CELA1 VGNC VGNC:27166
Macaca mulatta CELA1 VGNC VGNC:71152
Felis catus CELA1 VGNC VGNC:60743
Canis familiaris CELA1 VGNC VGNC:39092
Mus musculus CELA1 MGD MGI:95314
Rattus norvegicus CELA1 RGD RGD:2547
Others CELA1 NCBI