Manba - mannosidase, beta A, lysosomal Gene

Also Known as Bmn; 2410030O07Rik; B930014J03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110173

Summary

Enables beta-mannosidase activity. Involved in glycoprotein catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system; ear; genitourinary system; heart; and nervous system. Used to study beta-mannosidosis. Human ortholog(s) of this gene implicated in beta-mannosidosis. Orthologous to human MANBA (mannosidase beta). [provided by Alliance of Genome Resources, Apr 2022]

Manba Products (1)

mRNA Protein Name
NM_027288.3 NP_081564.3 beta-mannosidase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-mannosidase activity IDA
IDA: Inferred from direct assay
3447593 MGI
enables beta-mannosidase activity IMP
IMP: Inferred from mutant phenotype
33441424 MGI
enables hydrolase activity IDA
IDA: Inferred from direct assay
19710420 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within glycoprotein catabolic process IDA
IDA: Inferred from direct assay
3447593 MGI
involved in glycoprotein catabolic process IDA
IDA: Inferred from direct assay
16377659 MGI
involved in oligosaccharide catabolic process IDA
IDA: Inferred from direct assay
3447593 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
19710420 MGI
is active in lysosomal lumen IDA
IDA: Inferred from direct assay
29773673 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-mannosidase

  • lysosomal beta A mannosidase

  • mannanase

  • mannase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0020A Tos-Gly-Pro-Arg-ANBA-IPA acetate 99.20% Unkown
HY-RS08013 MANBA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P2858 β-Mannosidase / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Manba NCBI NCBI:4126