Glra3 - glycine receptor, alpha 3 subunit Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110304

Summary

Predicted to enable glycine-gated chloride ion channel activity. Predicted to contribute to extracellularly glycine-gated Chloride Channel activity and glycine binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within glutamate receptor clustering. Located in GABA-ergic synapse and glutamatergic synapse. Is active in glycinergic synapse. Is expressed in central nervous system and eye. Orthologous to human GLRA3 (glycine receptor alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Glra3 Products (2)

mRNA Protein Name
NM_001368774.2 NP_001355703.1 glycine receptor subunit alpha-3 isoform 2 precursor
NM_080438.4 NP_536686.3 glycine receptor subunit alpha-3 isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
26851771 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
26851771 MGI
Cellular Component GO Annotation Evidence References Source
is active in glycinergic synapse IDA
IDA: Inferred from direct assay
26851771 MGI
is active in glycinergic synapse IMP
IMP: Inferred from mutant phenotype
26851771 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
26851771 MGI
is active in presynaptic membrane IMP
IMP: Inferred from mutant phenotype
26851771 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine receptor subunit alpha-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05494 GLRA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glra3 NCBI NCBI:8001