FITM2 - fat storage inducing transmembrane protein 2 Gene

Homo sapiens

Also known as Fit2; SIDDIS; C20orf142; dJ881L22.2

Gene ID: 128486 | Gene type: protein coding

About FITM2

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:44,302,840-44,311,202 (from NCBI)

This gene has 1 transcript (splice variant), 205 orthologues, 1 paralogue and is associated with 1 phenotype. Broad expression in heart (RPKM 23.3), fat (RPKM 9.0) and 21 other tissues.

Summary

FIT2 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008]

FITM2 Products(1)

mRNA	Protein	Name
NM_001080472.4	NP_001073941.1	acyl-coenzyme A diphosphatase FITM2

FITM2 Protein Structure

Scs3p

0
100
200
262 a.a.

Protein Preferred Names

Protein Names

acyl-coenzyme A diphosphatase FITM2

fat-inducing protein 2

Related Diseases

Diseases

Alias

Siddiqi Syndrome

SIDDIS

Deafness, Dystonia, Developmental Delay, And Poor Growth

Sexual Sadism

Sadism

Dystonia

Dystonic Disease	Dystonic Disorder
Dystonia Disorders	Neuroleptic Dyskinesia

Mohr-Tranebjaerg Syndrome

Deafness-Dystonia-Optic Neuronopathy Syndrome	Jensen Syndrome
Deafness Dystonia Syndrome	MTS
Dds	Deafness-Dystonia-Optic Atrophy Syndrome
Deafness Syndrome, Progressive, With Blindness, Dystonia, Fractures, And Mental Deficiency	Opticoacoustic Nerve Atrophy With Dementia
Dystonia-Deafness Syndrome	Ddp
Ddon Syndrome	Mohr-Tranebjærg Syndrome
Deafness Dystonia Optic Atrophy Syndrome	Deafness Dystonia Optic Neuronopathy Syndrome
Dystonia Deafness Syndrome	Ddon
Deafness - Dystonia - Optic Neuronopathy Syndrome	Deafness-Dystonia-Optic Neuronopathy Syndrome
Hearing Loss-Dystonia-Optic Neuronopathy Syndrome	Dfn-1
X-Linked Progressive Deafness Type 1

Ichthyosis

Ichthyoses	Non-Syndromic Ichthyosis
Congenital Ichthyosis

Congenital Generalized Lipodystrophy

Berardinelli-Seip Congenital Lipodystrophy	Berardinelli-Seip Syndrome
Brunzell Syndrome	Bscl
Generalized Lipodystrophy	Lipodystrophy, Congenital Generalized
Seip Syndrome	Total Lipodystrophy
Cgl	Lipoatrophic Diabetes
Lipodystrophy, Generalized, Congenital	Familial Generalized Lipodystrophy
Congenital Generalized Lipodystrophy Type 2	Lipoatrophic Diabetes Mellitus
Familial Partial Lipodystrophy, Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04953	FITM2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FITM2	VGNC	VGNC:80100
Rattus norvegicus	FITM2	RGD	RGD:1307696
Bos taurus	FITM2	VGNC	VGNC:29016
Canis familiaris	FITM2	VGNC	VGNC:54304
Mus musculus	FITM2	MGD	MGI:2444508
Macaca mulatta	FITM2	VGNC	VGNC:84768

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