2. Gene
  3. TPRA1 - transmembrane protein adipocyte associated 1 Gene

TPRA1 - transmembrane protein adipocyte associated 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GPR175; TPRA40; TMEM227

Gene ID: 131601 | Gene type: protein coding

About TPRA1

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:127,571,232-127,598,231 (from NCBI)

This gene has 12 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in placenta (RPKM 7.3), endometrium (RPKM 6.7) and 25 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within embryonic cleavage and negative regulation of mitotic cell cycle phase transition. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TPRA1 Products(9)

mRNA Protein Name
NM_001136053.4 NP_001129525.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001142646.4 NP_001136118.1 transmembrane protein adipocyte-associated 1 isoform 2
NM_001353001.2 NP_001339930.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353002.2 NP_001339931.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353003.2 NP_001339932.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353004.2 NP_001339933.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353005.2 NP_001339934.1 transmembrane protein adipocyte-associated 1 isoform 1
NM_001353006.2 NP_001339935.1 transmembrane protein adipocyte-associated 1 isoform 3
NM_001353007.2 NP_001339936.1 transmembrane protein adipocyte-associated 1 isoform 4

TPRA1 Protein Structure

Tmemb_40

Tmemb_40: Predicted membrane protein (35 - 312)

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  • 300
  • 373 a.a.
Protein Preferred Names Protein Names

transmembrane protein adipocyte-associated 1

G protein-coupled receptor 175

Related Diseases

Diseases Alias
Fox-Fordyce Disease

Fox Fordyce Disease

Apocrine Miliaria

Fox-Fordyce Syndrome

Miliaria, Apocrine
Dyschromatosis Universalis Hereditaria

Duh
Atrophic Rhinitis

Rhinitis, Atrophic

Ozena

Rhinitis Sicca

Dry Rhinitis

Ozaena
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14947 TPRA1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TPRA1 VGNC VGNC:79848
Mus musculus TPRA1 MGD MGI:1345190
Felis catus TPRA1 VGNC VGNC:66484
Canis familiaris TPRA1 VGNC VGNC:47752
Rattus norvegicus TPRA1 RGD RGD:620858
Bos taurus TPRA1 VGNC VGNC:54506