SHROOM1 - shroom family member 1 Gene

Homo sapiens

Also known as APXL2

Gene ID: 134549 | Gene type: protein coding

About SHROOM1

Cytogenetic location: 5q31.1 Genomic coordinates (GRCh38): 5:132,822,141-132,830,647 (from NCBI)

This gene has 8 transcripts (splice variants), 195 orthologues and 3 paralogues. Broad expression in prostate (RPKM 16.8), urinary bladder (RPKM 6.1) and 15 other tissues.

Summary

SHROOM family members play diverse roles in the development of the nervous system and other tissues (Hagens et al., 2006 [PubMed 16615870]).[supplied by OMIM, Mar 2008]

SHROOM1 Products(3)

mRNA	Protein	Name
NM_001172700.2	NP_001166171.1	protein Shroom1 isoform 1
NM_001410779.1	NP_001397708.1	protein Shroom1 isoform 3
NM_133456.3	NP_597713.2	protein Shroom1 isoform 2

SHROOM1 Protein Structure

ASD1

ASD2

0
200
400
600
800
852 a.a.

Protein Preferred Names

Protein Names

protein Shroom1

apical protein 2

Related Diseases

Diseases

Alias

Retroperitoneum Carcinoma

Retroperitoneal Cancer	Malignant Neoplasm Of Retroperitoneum And Peritoneum
Retroperitoneal Neoplasms	Carcinoma Of Retroperitoneum
Carcinoma Of The Retroperitoneum	Malignant Neoplasm Of Retroperitoneum
Malignant Retroperitoneal Cancer	Malignant Tumor Of Peritoneum And Retroperitoneum
Neoplasm Of Retroperitoneum	Neoplasm Of The Retroperitoneum
Retroperitoneal Neoplasm	Tumor Of Retroperitoneum
Malignant Retroperitoneal Tumour	Primary Malignant Neoplasm Of Retroperitoneum
Retroperitoneum Cancer

Transient Arthritis

Deafness, Autosomal Recessive 100

DFNB100	Autosomal Recessive Nonsyndromic Deafness 100
Autosomal Recessive Deafness 100	Deafness, Autosomal Recessive, 100

Atrial Septal Defect 2

ASD2	Atrial Heart Septal Defect 2
Atrial Septal Defect-2	Asd Ii
Septal Defect, Atrial, Type 2

Palmoplantar Keratoderma, Punctate Type Ia

Keratosis Palmoplantaris Papulosa	Punctate Palmoplantar Keratoderma Type I
Ppkp1	Keratodermia Palmoplantaris Papulosa, Buschke-Fischer-Brauer Type
PPKP1A	Kppp1
Punctate Palmoplantar Keratoderma Type 1	Palmoplantar Keratoderma, Punctate Type 1a
Palmoplantar Keratoderma, Punctate Type I	Keratoderma, Palmoplantar, Punctate Type Ia
Punctate Palmoplantar Keratoderma Type 1a	Punctate Palmoplantar Keratoderma Type 1b
Brauer-Buschke-Fischer Syndrome	Keratoderma, Palmoplantar Punctate Type 1
Type I Punctate Palmoplantar Keratoderma	Buschke-Fischer-Brauer Syndrome
Keratoderma, Palmoplantar, Punctate 1a	Keratodermia Palmoplantaris Papulosa Buschke-Fischer-Brauer Type
Keratosis Punctate Palmoplantaris Buschke-Fisher-Brauer Type	Punctate Palmoplantar Keratoderma Type Ia
Keratoderma, Palmoplantar, Punctate Type 1	Keratoderma, Palmoplantar, Punctate, Type Ia

Retroperitoneal Sarcoma

Atrial Heart Septal Defect

Atrial Septal Defect	Atrial Septal Defects
Atrioseptal Defect	Auricular Septal Defect
Congenital Atrial Septal Defect	Interatrial Septal Defect
Interauricular Septal Defect	Heart Septal Defects, Atrial
Septal Defect, Atrial

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12884	SHROOM1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SHROOM1	VGNC	VGNC:65133
Canis familiaris	SHROOM1	VGNC	VGNC:46156
Mus musculus	SHROOM1	MGD	MGI:1919024
Bos taurus	SHROOM1	VGNC	VGNC:34608
Macaca mulatta	SHROOM1	VGNC	VGNC:77299
Rattus norvegicus	SHROOM1	RGD	RGD:1308066

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