LETM2 - leucine zipper and EF-hand containing transmembrane protein 2 Gene

Also Known as SLC55A2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 137994

About LETM2

This gene has 15 transcripts (splice variants), 214 orthologues and 2 paralogues. Broad expression in testis (RPKM 3.0), brain (RPKM 0.6) and 14 other tissues.

Summary

Predicted to enable ribosome binding activity. Predicted to be involved in cellular metal ion homeostasis. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LETM2 Products (9)

mRNA Protein Name
NM_001199659.3 NP_001186588.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 1
NM_001199660.3 NP_001186589.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 3
NM_001286787.2 NP_001273716.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 3
NM_001286819.2 NP_001273748.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 4
NM_001286821.2 NP_001273750.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 5
NM_001330515.2 NP_001317444.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 6
NM_001363204.1 NP_001350133.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 7 precursor
NM_001363205.1 NP_001350134.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 3
NM_144652.4 NP_653253.1 LETM1 domain-containing protein LETM2, mitochondrial isoform 2

LETM2 Protein Structure

LETM1

LETM1: LETM1-like protein (120 - 386)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 491 a.a.
Protein Preferred Names Protein Names

LETM1 domain-containing protein LETM2, mitochondrial

  • LETM1 and EF-hand domain-containing protein 2

Related Diseases

Diseases Alias
Acute Hemorrhagic Leukoencephalitis

  • Ahl

  • Acute Haemorrhagic Leucoencephalitis Of Weston Hurst

  • Leukoencephalitis, Acute Hemorrhagic

  • Acute Hemorrhagic Encephalomyelitis

  • Acute Necrotizing Hemorrhagic Leukoencephalitis

  • Weston-Hurst Syndrome

  • Ahle

  • Acute Haemorrhagic Leucoencephalitis

  • Hurst Disease

  • Acute Haemorrhagic Leukoencephalitis, Postimmunization Or Postvaccinal

  • Postimmunization Or Postvaccinal Leukoencephalopathy
Wolf-Hirschhorn Syndrome

  • Pitt-Rogers-Danks Syndrome

  • WHS

  • Chromosome 4p16.3 Deletion Syndrome

  • Wittwer Syndrome

  • 4p- Syndrome

  • Pitt Syndrome

  • 4p Deletion Syndrome

  • Distal Deletion 4p

  • Distal Monosomy 4p

  • Telomeric Deletion 4p

  • Prds

  • 4p Syndrome

  • Chromosome 4p Syndrome

  • Microcephaly, Iugr, Hypertelorism, Ptosis, Iris Coloboma, Hooked Nose, External Ear Dysplasia, Psychomotor Retardation

  • Wolf Syndrome

  • Chromosome 4p Deletion Syndrome

  • Chromosome 4p Monosomy

  • Del Syndrome

  • Monosomy 4p

  • Partial Monosomy 4p

  • Chromosome 4 Short Arm Deletion
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07598 LETM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus LETM2 MGD MGI:2444979
Canis familiaris LETM2 VGNC VGNC:42642
Macaca mulatta LETM2 VGNC VGNC:74046
Rattus norvegicus LETM2 RGD RGD:1311220
Felis catus LETM2 VGNC VGNC:63215
Others LETM2 NCBI