Ercc3 - excision repair cross-complementing rodent repair deficiency, complementation group 3 Gene
Also Known as XPB; Ercc-3; BTF2 p89
Species: Mus musculus
Summary
Enables ATP hydrolysis activity and promoter-specific chromatin binding activity. Acts upstream of or within UV protection and transcription elongation from RNA polymerase I promoter. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex; nucleotide-excision repair factor 3 complex; and transcription preinitiation complex. Is expressed in several structures, including brain; eye; liver; oral region epithelium; and tooth. Used to study xeroderma pigmentosum group B. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; photosensitive trichothiodystrophy 2; trichothiodystrophy; xeroderma pigmentosum; and xeroderma pigmentosum group B. Orthologous to human ERCC3 (ERCC excision repair 3, TFIIH core complex helicase subunit). [provided by Alliance of Genome Resources, Apr 2022]
Ercc3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_133658.2 | NP_598419.1 | general transcription and DNA repair factor IIH helicase subunit XPB |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
general transcription and DNA repair factor IIH helicase subunit XPB |
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|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-141549 | BPK-21 | 99.56% | Unkown | |
| HY-D2331 | ZL-12A probe | 99.71% | Unkown | |
| HY-RS04480 | ERCC3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19680 | Ercc3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26173 | Ercc3 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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