Prg2 - proteoglycan 2, bone marrow Gene

Also Known as MBP; EMBP; mMBP; mMBP-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19074

Summary

Predicted to enable carbohydrate binding activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Acts upstream of or within defense response to nematode; negative regulation of interleukin-10 production; and positive regulation of interleukin-4 production. Located in collagen-containing extracellular matrix. Is expressed in several structures, including immune system; liver; lung; and testis. Orthologous to human PRG2 (proteoglycan 2, pro eosinophil major basic protein). [provided by Alliance of Genome Resources, Apr 2022]

Prg2 Products (1)

mRNA Protein Name
NM_008920.4 NP_032946.1 bone marrow proteoglycan precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within defense response to nematode IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of interleukin-10 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of macrophage cytokine production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of or within negative regulation of interleukin-10 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of or within negative regulation of macrophage cytokine production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of or within positive regulation of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bone marrow proteoglycan

  • BMPG

  • major basic protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11088 PRG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11479 PXDN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17666 Ptgr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19939 Prg2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20464 Plpp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26441 Prg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prg2 NCBI NCBI:5553