PPP1R35 - protein phosphatase 1 regulatory subunit 35 Gene

Homo sapiens

Also known as C7orf47

Gene ID: 221908 | Gene type: protein coding

About PPP1R35

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,435,282-100,436,698 (from NCBI)

This gene has 5 transcripts (splice variants) and 98 orthologues. Broad expression in testis (RPKM 18.3), spleen (RPKM 14.1) and 25 other tissues.

Summary

Predicted to enable Phosphatase binding activity and protein Phosphatase Inhibitor activity. Predicted to be involved in negative regulation of Phosphatase activity. [provided by Alliance of Genome Resources, Apr 2022]

PPP1R35 Products(2)

mRNA	Protein	Name
NM_001346938.2	NP_001333867.1	protein phosphatase 1 regulatory subunit 35 isoform 2
NM_145030.4	NP_659467.1	protein phosphatase 1 regulatory subunit 35 isoform 1

PPP1R35 Protein Structure

PPP1R35_C

0
100
200
253 a.a.

Protein Preferred Names

Protein Names

protein phosphatase 1 regulatory subunit 35

UPF0683 protein C7orf47

Related Diseases

Diseases

Alias

Bardet-Biedl Syndrome 1

BBS1	Bardet-Biedl Syndrome 1, Modifier Of
Bardet-Biedl Syndrome	BBS
Bardet-Biedl Syndrome, Type 1	Laurence-Moon-Bardet-Biedl Syndrome

Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly	Mcph
True Microcephaly	Microcephalia Vera
Microcephaly Vera	Microcephaly Primary Hereditary
Microcephaly, Primary, Autosomal Recessive	Primary Microcephaly

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10997	PPP1R35 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PPP1R35	VGNC	VGNC:76331
Canis familiaris	PPP1R35	VGNC	VGNC:44893
Mus musculus	PPP1R35	MGD	MGI:1922853
Felis catus	PPP1R35	VGNC	VGNC:107810
Rattus norvegicus	PPP1R35	RGD	RGD:1584367

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