2. Gene
  3. COPZ1 - COPI coat complex subunit zeta 1 Gene

COPZ1 - COPI coat complex subunit zeta 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as COPZ; CGI-120; HSPC181; zeta-COP; zeta1-COP

Gene ID: 22818 | Gene type: protein coding

About COPZ1

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:54,325,131-54,351,846 (from NCBI)

This gene has 18 transcripts (splice variants), 217 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 49.0), colon (RPKM 30.9) and 25 other tissues.

Summary

This gene encodes a subunit of the cytoplasmic coatamer protein complex, which is involved in Autophagy and intracellular protein trafficking. The coatomer protein complex is comprised of seven subunits and functions as the coat protein of coat protein complex (COP)I-vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

COPZ1 Products(4)

mRNA Protein Name
NM_001271734.2 NP_001258663.1 coatomer subunit zeta-1 isoform 2
NM_001271735.2 NP_001258664.1 coatomer subunit zeta-1 isoform 3
NM_001271736.2 NP_001258665.1 coatomer subunit zeta-1 isoform 4
NM_016057.3 NP_057141.1 coatomer subunit zeta-1 isoform 1

COPZ1 Protein Structure

Clat_adaptor_s

Clat_adaptor_s: Clathrin adaptor complex small chain (12 - 151)

  • 0
  • 100
  • 177 a.a.
Protein Preferred Names Protein Names

coatomer subunit zeta-1

coatomer protein complex subunit zeta 1

Recombinant COPZ1 Proteins

Cat. No. Product Name Accession Purity
HY-P76847 COPZ1 Protein, Rat (His) P61923 (M1-R177) ≥95%

Related Diseases

Diseases Alias
Menkes Disease

Copper Transport Disease

Menkes Syndrome

MNK

Kinky Hair Disease

Steely Hair Disease

Menkes Kinky-Hair Syndrome

Mk

Steely Hair Syndrome

Menkea Syndrome

Md

Menkes Kinky Hair Syndrome

Hypocupremia, Congenital

Kinky Hair Syndrome

X-Linked Copper Deficiency

Menkes Kinky Hair Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03034 COPZ1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus COPZ1 MGD MGI:1929063
Macaca mulatta COPZ1 VGNC VGNC:71318
Rattus norvegicus COPZ1 RGD RGD:1306154
Bos taurus COPZ1 VGNC VGNC:27607
Felis catus COPZ1 VGNC VGNC:83540
Others COPZ1 NCBI