2. Gene
  3. Slc30a8 - solute carrier family 30 (zinc transporter), member 8 Gene

Slc30a8 - solute carrier family 30 (zinc transporter), member 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ZnT8; ZnT-8; C820002P14Rik

Gene ID: 239436 | Gene type: protein coding

About Slc30a8

Summary

Enables protein homodimerization activity. Involved in cellular zinc ion homeostasis; Insulin secretion; and response to glucose. Located in cytoplasmic vesicle. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC30A8 (solute carrier family 30 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc30a8 Products(1)

mRNA Protein Name
NM_172816.4 NP_766404.1 zinc transporter 8
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
19095428 MGI
enables zinc ion transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
19542200 MGI
Biological Process GO Annotation Evidence Reference Source
NOT involved in glucose homeostasis IMP
IMP: Inferred from mutant phenotype
19450229 MGI
involved in insulin processing IMP
IMP: Inferred from mutant phenotype
19542200 MGI
involved in insulin secretion IMP
IMP: Inferred from mutant phenotype
19450229 MGI
involved in intracellular zinc ion homeostasis IMP
IMP: Inferred from mutant phenotype
19450229 MGI
involved in response to glucose IMP
IMP: Inferred from mutant phenotype
19450229 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
19095428 MGI
is active in secretory granule IDA
IDA: Inferred from direct assay
20424817 MGI
is active in secretory granule membrane IDA
IDA: Inferred from direct assay
20424817 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc transporter 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13186 SLC30A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc30a8 NCBI NCBI:169026