2. Gene
  3. Kif20b - kinesin family member 20B Gene

Kif20b - kinesin family member 20B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MPP1; 33cex; magoo; Mphosph1; C330014J10Rik

Gene ID: 240641 | Gene type: protein coding

About Kif20b

Summary

Predicted to enable several functions, including ATP hydrolysis activity; WW domain binding activity; and plus-end-directed microtubule motor activity. Involved in several processes, including positive regulation of mitotic cytokinetic process; positive regulation of neuron migration; and protein localization to microtubule. Acts upstream of or within neural tube closure; regulation of establishment of protein localization; and regulation of neuron migration. Located in several cellular components, including midbody; perinuclear region of cytoplasm; and spindle midzone. Is expressed in cerebral cortex marginal layer; cerebral cortex ventricular layer; cortical plate; and cortical subplate. Used to study microcephaly. Orthologous to human KIF20B (Kinesin family member 20B). [provided by Alliance of Genome Resources, Apr 2022]

Kif20b Products(2)

mRNA Protein Name
NM_001362434.1 NP_001349363.1 kinesin-like protein KIF20B isoform 2
NM_183046.2 NP_898867.1 kinesin-like protein KIF20B isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23864681 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
15755804 MGI
involved in neuron projection morphogenesis IMP
IMP: Inferred from mutant phenotype
23864681 MGI
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
24173802 MGI
involved in positive regulation of intracellular protein transport IMP
IMP: Inferred from mutant phenotype
23864681 MGI
involved in positive regulation of mitotic cytokinetic process IMP
IMP: Inferred from mutant phenotype
24173802 MGI
involved in positive regulation of neuron migration IMP
IMP: Inferred from mutant phenotype
23864681 MGI
involved in protein localization to microtubule IMP
IMP: Inferred from mutant phenotype
23864681 MGI
acts upstream of or within regulation of establishment of cell polarity IGI
IGI: Inferred from genetic interaction
23864681 MGI
involved in regulation of establishment of cell polarity IMP
IMP: Inferred from mutant phenotype
23864681 MGI
acts upstream of or within regulation of establishment of protein localization IDA
IDA: Inferred from direct assay
23864681 MGI
acts upstream of or within regulation of neuron migration IGI
IGI: Inferred from genetic interaction
23864681 MGI
Cellular Component GO Annotation Evidence Reference Source
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
23864681 MGI
located in midbody IDA
IDA: Inferred from direct assay
23864681 MGI
located in nucleus IDA
IDA: Inferred from direct assay
24173802 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
23864681 MGI
located in spindle midzone IDA
IDA: Inferred from direct assay
24173802 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF20B

M-phase phosphoprotein 1

N-6 kinesin

kinesin-related motor interacting with PIN1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07273 KIF20B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif20b NCBI NCBI:9585