2. Gene
  3. Neu4 - sialidase 4 Gene

Neu4 - sialidase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 9330166I04

Gene ID: 241159 | Gene type: protein coding

About Neu4

Summary

Enables exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. Involved in ganglioside catabolic process; glycoprotein catabolic process; and negative regulation of neuron projection development. Located in neuron projection and plasma membrane. Is expressed in brain. Orthologous to human NEU4 (neuraminidase 4). [provided by Alliance of Genome Resources, Apr 2022]

Neu4 Products(2)

mRNA Protein Name
NM_001310769.1 NP_001297698.1 sialidase-4 isoform 1
NM_173772.3 NP_776133.1 sialidase-4 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables exo-alpha-sialidase activity IDA
IDA: Inferred from direct assay
14637003 MGI
Biological Process GO Annotation Evidence Reference Source
involved in ganglioside catabolic process IDA
IDA: Inferred from direct assay
19506080 MGI
involved in glycoprotein catabolic process IDA
IDA: Inferred from direct assay
19506080 MGI
involved in negative regulation of neuron projection development IDA
IDA: Inferred from direct assay
22393058 MGI
Cellular Component GO Annotation Evidence Reference Source
located in neuron projection IDA
IDA: Inferred from direct assay
22393058 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
22393058 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialidase-4

N-acetyl-alpha-neuraminidase 4

neuraminidase 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-125798 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid Inhibitor ≥99.0% Unkown
HY-161943 NEU3-IN-1 98.74% Unkown
HY-RS09218 NEU4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neu4 NCBI NCBI:129807