Neu4 - sialidase 4 Gene

Also Known as 9330166I04

Species: Mus musculus

Gene Type: protein coding
Gene ID: 241159

Summary

Enables exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. Involved in ganglioside catabolic process; glycoprotein catabolic process; and negative regulation of neuron projection development. Located in neuron projection and plasma membrane. Is expressed in brain. Orthologous to human NEU4 (neuraminidase 4). [provided by Alliance of Genome Resources, Apr 2022]

Neu4 Products (2)

mRNA Protein Name
NM_001310769.1 NP_001297698.1 sialidase-4 isoform 1
NM_173772.3 NP_776133.1 sialidase-4 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables exo-alpha-sialidase activity IDA
IDA: Inferred from direct assay
14637003 MGI
Biological Process GO Annotation Evidence References Source
involved in ganglioside catabolic process IDA
IDA: Inferred from direct assay
19506080 MGI
involved in glycoprotein catabolic process IDA
IDA: Inferred from direct assay
19506080 MGI
involved in negative regulation of neuron projection development IDA
IDA: Inferred from direct assay
22393058 MGI
Cellular Component GO Annotation Evidence References Source
located in neuron projection IDA
IDA: Inferred from direct assay
22393058 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
22393058 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialidase-4

  • N-acetyl-alpha-neuraminidase 4

  • neuraminidase 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-125798 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid Inhibitor ≥99.0% Unkown
HY-161943 NEU3-IN-1 98.74% Unkown
HY-RS09218 NEU4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neu4 NCBI NCBI:129807