2. Gene
  3. Frem2 - Fras1 related extracellular matrix protein 2 Gene

Frem2 - Fras1 related extracellular matrix protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as my; ne; nv1; Gm409; b2b1562Clo; 6030440P17Rik; 8430406N05Rik

Gene ID: 242022 | Gene type: protein coding

About Frem2

Summary

Predicted to enable metal ion binding activity. Involved in eye development. Acts upstream of or within animal organ development; embryonic digit morphogenesis; and morphogenesis of an epithelium. Located in basement membrane. Is expressed in several structures, including alimentary system; central nervous system; intraembryonic coelom; sensory organ; and skin. Used to study Fraser syndrome and isolated cryptophthalmia. Human ortholog(s) of this gene implicated in Fraser syndrome 2 and isolated cryptophthalmia. Orthologous to human FREM2 (FRAS1 related extracellular matrix 2). [provided by Alliance of Genome Resources, Apr 2022]

Frem2 Products(1)

mRNA Protein Name
NM_172862.3 NP_766450.2 FRAS1-related extracellular matrix protein 2 precursor
Protein Preferred Names Protein Names

FRAS1-related extracellular matrix protein 2

ECM3 homolog

NV domain containing protein NV1

NV domain-containing protein 1

Frem2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Frem2 Q6NVD0 Fras1 Mus musculus Q80T14
Anti Tag CoIP
16880404
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05093 FREM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Frem2 NCBI NCBI:341640