Slc1a7 - solute carrier family 1 (glutamate transporter), member 7 Gene

Also Known as Eaat5; A930031E15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242607

Summary

Enables L-glutamate transmembrane transporter activity. Acts upstream of or within L-glutamate transmembrane transport. Located in plasma membrane. Is integral component of presynaptic membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in several structures, including cerebellum; mesenchyme of metanephros; and retina nuclear layer. Orthologous to human SLC1A7 (solute carrier family 1 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc1a7 Products (1)

mRNA Protein Name
NM_146255.3 NP_666367.3 excitatory amino acid transporter 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-glutamate transmembrane transporter activity IDA
IDA: Inferred from direct assay
24307171 MGI
enables extracellularly glutamate-gated chloride channel activity IDA
IDA: Inferred from direct assay
16973698 MGI
enables glutamate:sodium symporter activity IDA
IDA: Inferred from direct assay
16973698 MGI
enables monoatomic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
24307171 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within L-glutamate transmembrane transport IDA
IDA: Inferred from direct assay
24307171 MGI
involved in L-glutamate transmembrane transport IDA
IDA: Inferred from direct assay
16973698 MGI
involved in chloride transmembrane transport IDA
IDA: Inferred from direct assay
32233906 MGI
acts upstream of or within monoatomic anion transmembrane transport IDA
IDA: Inferred from direct assay
24307171 MGI
Cellular Component GO Annotation Evidence References Source
located in axon terminus IDA
IDA: Inferred from direct assay
16973698 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23049999 MGI
located in photoreceptor cell terminal bouton IDA
IDA: Inferred from direct assay
16973698 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24307171 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
23049999 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
23049999 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

excitatory amino acid transporter 5

  • solute carrier family 1 member 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13058 SLC1A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16831 Slc1a5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21935 Slc1a7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23273 Slc1a5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28451 Slc1a7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc1a7 NCBI NCBI:6512