Slc29a4 - solute carrier family 29 (nucleoside transporters), member 4 Gene

Mus musculus

Also known as ENT4; mPMAT

Gene ID: 243328 | Gene type: protein coding

About Slc29a4

Summary

Enables several functions, including monoamine transmembrane transporter activity; neurotransmitter transmembrane transporter activity; and toxin transmembrane transporter activity. Involved in several processes, including monoamine transport; toxin transport; and xenobiotic transport. Located in apical plasma membrane and basolateral plasma membrane. Is expressed in brain and male reproductive gland or organ. Orthologous to human SLC29A4 (solute carrier family 29 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc29a4 Products(1)

mRNA	Protein	Name
NM_146257.2	NP_666369.1	equilibrative nucleoside transporter 4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables monoamine transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	20858707	MGI
enables monoatomic cation transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	23255610	MGI
enables neurotransmitter transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	20858707	MGI
enables toxin transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	23255610	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in adenosine transport	IDA IDA: Inferred from direct assay	16873718	MGI
involved in cellular detoxification	IMP IMP: Inferred from mutant phenotype	23255610	MGI
involved in dopamine transport	IMP IMP: Inferred from mutant phenotype	23255610	MGI
involved in dopamine uptake	IMP IMP: Inferred from mutant phenotype	20858707	MGI
involved in monoatomic cation transmembrane transport	IMP IMP: Inferred from mutant phenotype	23255610	MGI
involved in neurotransmitter transport	IMP IMP: Inferred from mutant phenotype	20858707	MGI
involved in norepinephrine uptake	IMP IMP: Inferred from mutant phenotype	20858707	MGI
involved in serotonin transport	IMP IMP: Inferred from mutant phenotype	23255610	MGI
involved in serotonin uptake	IMP IMP: Inferred from mutant phenotype	20858707	MGI
involved in xenobiotic transport	IMP IMP: Inferred from mutant phenotype	23255610	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	23255610	MGI
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	26376205	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

equilibrative nucleoside transporter 4

solute carrier family 29 member 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13156	SLC29A4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc29a4	NCBI	NCBI:222962

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