Tshz3 - teashirt zinc finger family member 3 Gene

Mus musculus

Also known as Tsh3; Zfp537; mKIAA1474; teashirt3; A630038G13Rik

Gene ID: 243931 | Gene type: protein coding

About Tshz3

Summary

Predicted to enable DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and chromatin binding activity. Involved in several processes, including positive regulation of synaptic transmission; regulation of respiratory gaseous exchange by nervous system process; and smooth muscle tissue development. Acts upstream of or within several processes, including kidney development; positive regulation of smooth muscle cell differentiation; and sensory perception of touch. Located in mitochondrion. Is expressed in genitourinary system and peripheral nervous system. Orthologous to human TSHZ3 (teashirt zinc finger homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Tshz3 Products(1)

mRNA	Protein	Name
NM_172298.3	NP_758502.1	teashirt homolog 3

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19343227	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within in utero embryonic development	IMP IMP: Inferred from mutant phenotype	18776146	MGI
acts upstream of or within kidney morphogenesis	IMP IMP: Inferred from mutant phenotype	18776146	MGI
involved in kidney smooth muscle cell differentiation	IMP IMP: Inferred from mutant phenotype	18776146	MGI
involved in long-term synaptic potentiation	IMP IMP: Inferred from mutant phenotype	27668656	MGI
involved in lung development	IMP IMP: Inferred from mutant phenotype	18776146	MGI
involved in metanephros development	IEP IEP: Inferred from expression pattern	18776146	MGI
acts upstream of or within musculoskeletal movement	IMP IMP: Inferred from mutant phenotype	18776146	MGI
acts upstream of or within positive regulation of smooth muscle cell differentiation	IMP IMP: Inferred from mutant phenotype	18776146	MGI
involved in positive regulation of synaptic transmission, glutamatergic	IMP IMP: Inferred from mutant phenotype	27668656	MGI
involved in regulation of respiratory gaseous exchange by nervous system process	IMP IMP: Inferred from mutant phenotype	20631175	MGI
acts upstream of or within sensory perception of touch	IMP IMP: Inferred from mutant phenotype	18776146	MGI
acts upstream of or within smooth muscle tissue development	IMP IMP: Inferred from mutant phenotype	18776146	MGI
involved in ureter smooth muscle cell differentiation	IMP IMP: Inferred from mutant phenotype	18776146	MGI
acts upstream of or within ureteric bud development	IMP IMP: Inferred from mutant phenotype	18776146	MGI
involved in ureteric peristalsis	IMP IMP: Inferred from mutant phenotype	18776146	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

teashirt homolog 3

teashirt 3

zinc finger protein 537

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15150	TSHZ3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tshz3	NCBI	NCBI:57616

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