Oprd1 - opioid receptor, delta 1 Gene

Rattus norvegicus

Gene ID: 24613 | Gene type: protein coding

About Oprd1

Summary

Enables G protein-coupled enkephalin receptor activity and receptor serine/threonine kinase binding activity. Involved in several processes, including eating behavior; Phospholipase C-activating G protein-coupled receptor signaling pathway; and regulation of sensory perception of pain. Located in several cellular components, including dendrite membrane; membrane raft; and postsynaptic membrane. Is active in neuronal dense core vesicle and spine apparatus. Is integral component of postsynaptic density membrane; integral component of presynaptic membrane; and integral component of synaptic vesicle membrane. Used to study myocardial infarction. Orthologous to human OPRD1 (Opioid Receptor delta 1). [provided by Alliance of Genome Resources, Apr 2022]

Oprd1 Products(1)

mRNA	Protein	Name
NM_012617.1	NP_036749.1	delta-type opioid receptor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables G protein-coupled enkephalin receptor activity	IDA IDA: Inferred from direct assay	7519274	RGD
enables receptor serine/threonine kinase binding	IPI IPI: Inferred from physical interaction	28381559	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to growth factor stimulus	IEP IEP: Inferred from expression pattern	7562535	RGD
involved in eating behavior	IMP IMP: Inferred from mutant phenotype	15949635	RGD
involved in phospholipase C-activating G protein-coupled receptor signaling pathway	IDA IDA: Inferred from direct assay	9572309	RGD
involved in regulation of calcium ion transport	IMP IMP: Inferred from mutant phenotype	10493735	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	28511993	RGD
involved in response to nicotine	IEP IEP: Inferred from expression pattern	28509375	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in axon terminus	IDA IDA: Inferred from direct assay	9183814	RGD
located in dendrite membrane	IDA IDA: Inferred from direct assay	9183814	RGD
is active in neuronal dense core vesicle	IDA IDA: Inferred from direct assay	7666182	RGD
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	11312309	RGD
located in postsynaptic membrane	IDA IDA: Inferred from direct assay	9183814	RGD
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	7666182	RGD
is active in spine apparatus	IDA IDA: Inferred from direct assay	11312309	RGD
is active in synaptic vesicle membrane	IDA IDA: Inferred from direct assay	7666182	RGD
located in vesicle	IDA IDA: Inferred from direct assay	9183814	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

delta-type opioid receptor

D-OR-1	DOR-1
opioid receptor A

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-116163	ML350		/	Unkown
HY-RS09801	OPRD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Oprd1	NCBI	NCBI:4985

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