OPRD1 - opioid receptor delta 1 Gene

Also Known as DOP; DOR; DOR1; OPRD

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4985

About OPRD1

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:28,812,170-28,871,267 (from NCBI)

This gene has 1 transcript (splice variant), 253 orthologues and 17 paralogues. Low expression observed in reference dataset.

Summary

Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled Opioid Receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Is intrinsic component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OPRD1 Products (1)

mRNA Protein Name
NM_000911.4 NP_000902.3 delta-type opioid receptor

OPRD1 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (66 - 318)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
Protein Preferred Names Protein Names

delta-type opioid receptor

  • D-OR-1

OPRD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
OPRD1 P41143 SMAGP Homo sapiens Q0VAQ4
Validated Y2H
32296183
Intra
OPRD1 P41143 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra
OPRD1 P41143 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra
OPRD1 P41143 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra
OPRD1 P41143 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra
OPRD1 P41143 CTXN3 Homo sapiens Q4LDR2
Validated Y2H
32296183
Intra
OPRD1 P41143 SLC13A4 Homo sapiens Q9UKG4
Y2H Prey Pooling
32296183
Intra
OPRD1 P41143 SLC13A4 Homo sapiens Q9UKG4
Validated Y2H
32296183
Intra
OPRD1 P41143 SLC13A4 Homo sapiens Q9UKG4
Y2H Array
32296183
Intra
OPRD1 P41143 SLC12A7 Homo sapiens Q9Y666-2
Validated Y2H
32296183
Intra
OPRD1 P41143 CANX Homo sapiens P27824
Anti Tag CoIP
20528919
Intra
OPRD1 P41143 ATP2A2 Homo sapiens P16615
Anti Tag CoIP
20528919
Cross
OPRD1 P41143 ATP2A2 Sus scrofa P11607
Anti Tag CoIP
20528919
Cross: Cross-species interaction Intra: Intraspecies interaction

OPRD1 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P83372 delta Opioid Receptor Antibody (YA3117) WB, FC Human, Mouse, Rat

Related Diseases

Diseases Alias
Morphine Dependence
Heroin Dependence
Neonatal Abstinence Syndrome

  • Drug Withdrawal Syndrome In Newborn
Drug Dependence
Opiate Dependence

  • Opioid Dependence

  • Opioid Addiction

  • Opiate Addiction

  • Opioid Type Dependence

  • Opioid-Related Disorders

  • Opium Dependence

  • Narcotic Dependence

  • Intravenous Narcotism

  • Narcotism Nos

  • Oral Narcotism Nos
Substance Dependence
Pertussis

  • Whooping Cough

  • Bordetella Infections

  • Bordetella Infection

  • Bordetella Pertussis Infection

  • Wc - Whooping Cough

  • Whooping Cough Due To Unspecified Organism

  • Bordetellosis

  • Tussis Convulsiva

  • Whooping Cough, Unspecified Organism

  • Wc - [Whooping Cough]

  • Whooping Cough Due To B. Parapertussis

  • Infection Due To Bordetella Parapertussis
Opioid Abuse

  • Opioid-Related Disorders
Alcohol Dependence

  • Alcoholism

  • Alcohol Dependence, Susceptibility To

  • Alcohol Dependence, Protection Against

  • Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

  • Alcoholism, Susceptibility To

  • Alcoholic Intoxication, Chronic

  • Pharyngeal Neoplasms

  • Chronic Alcoholism

  • Dipsomania

  • Alcohol Addiction

  • Ethanol Dependence

  • Chronic Ethanolism

  • Chronic Alcoholic Disease Nos

  • Alcoholic Disease Nos

  • Alcoholic
Cocaine Dependence
Pain Agnosia

  • Analgesia
Agnosia

  • Dyspraxia

  • Primary Visual Agnosia

  • Dyspraxia Syndrome

  • Monomodal Visual Amnesia

  • Visual Amnesia

  • Agnosia, Primary Visual

  • Apraxias

  • Alexia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-116163 ML350 / Unkown
HY-RS09801 OPRD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus OPRD1 MGD MGI:97438
Felis catus OPRD1 VGNC VGNC:68632
Bos taurus OPRD1 VGNC VGNC:50539
Canis familiaris OPRD1 VGNC VGNC:44132
Macaca mulatta OPRD1 VGNC VGNC:75589
Rattus norvegicus OPRD1 RGD RGD:3233
Others OPRD1 NCBI