Ngef - neuronal guanine nucleotide exchange factor Gene

Also Known as Besh3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246217

Summary

Predicted to enable Ephrin Receptor binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including activation of GTPase activity; Ephrin Receptor signaling pathway; and negative regulation of dendritic spine morphogenesis. Predicted to be located in cytoplasm; growth cone; and membrane. Predicted to be active in glutamatergic synapse. Orthologous to human NGEF (neuronal guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Apr 2022]

Ngef Products (1)

mRNA Protein Name
NM_001136241.1 NP_001129713.1 ephexin-1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in postsynapse IDA
IDA: Inferred from direct assay
17143272 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephexin-1

  • brain-enriched SH3-domain protein Besh3

  • eph-interacting exchange protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09276 NGEF Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ngef NCBI NCBI:25791