Nsg1 - neuronal vesicle trafficking associated 1 Gene

Also Known as PEP1; Bsmrb; Neep21

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25247

Summary

Enables signaling receptor binding activity. Involved in several processes, including positive regulation of receptor recycling; postsynaptic neurotransmitter receptor cycle; and spontaneous synaptic transmission. Located in several cellular components, including endosome; lysosomal lumen; and trans-Golgi network membrane. Is active in glutamatergic synapse and postsynaptic endosome. Orthologous to human NSG1 (neuronal vesicle trafficking associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Nsg1 Products (1)

mRNA Protein Name
NM_024128.4 NP_077042.2 neuronal vesicle trafficking-associated protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ionotropic glutamate receptor binding IPI
IPI: Inferred from physical interaction
16037816 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12070131 RGD
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
16037816 RGD
Biological Process GO Annotation Evidence References Source
involved in endosomal transport IMP
IMP: Inferred from mutant phenotype
18299352 RGD
involved in positive regulation of receptor recycling IMP
IMP: Inferred from mutant phenotype
12070131 RGD
involved in postsynaptic neurotransmitter receptor cycle IMP
IMP: Inferred from mutant phenotype
15911354 RGD
involved in regulation of long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
15911354 RGD
involved in spontaneous synaptic transmission IMP
IMP: Inferred from mutant phenotype
15911354 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
28874679 RGD
located in early endosome IDA
IDA: Inferred from direct assay
28874679 RGD
located in early endosome membrane IDA
IDA: Inferred from direct assay
12070131 RGD
located in endosome IDA
IDA: Inferred from direct assay
18299352 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12070131 RGD
located in late endosome IDA
IDA: Inferred from direct assay
28874679 RGD
located in lysosomal lumen IDA
IDA: Inferred from direct assay
28874679 RGD
is active in postsynaptic endosome IDA
IDA: Inferred from direct assay
12070131 RGD
located in recycling endosome membrane IDA
IDA: Inferred from direct assay
12070131 RGD
located in somatodendritic compartment IDA
IDA: Inferred from direct assay
12070131 RGD
located in trans-Golgi network membrane IDA
IDA: Inferred from direct assay
28874679 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal vesicle trafficking-associated protein 1

  • brain neuron cytoplasmic protein 1/2

  • brain specific mRNA b

  • neuron specific gene family member 1

  • neuron-enriched endosomal protein of 21 kDa

  • neuron-specific protein family member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09593 NSG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsg1 NCBI NCBI:27065