Nsg1 - neuronal vesicle trafficking associated 1 Gene

Rattus norvegicus

Also known as PEP1; Bsmrb; Neep21

Gene ID: 25247 | Gene type: protein coding

About Nsg1

Summary

Enables signaling receptor binding activity. Involved in several processes, including positive regulation of receptor recycling; postsynaptic neurotransmitter receptor cycle; and spontaneous synaptic transmission. Located in several cellular components, including endosome; lysosomal lumen; and trans-Golgi network membrane. Is active in glutamatergic synapse and postsynaptic endosome. Orthologous to human NSG1 (neuronal vesicle trafficking associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Nsg1 Products(1)

mRNA	Protein	Name
NM_024128.4	NP_077042.2	neuronal vesicle trafficking-associated protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ionotropic glutamate receptor binding	IPI IPI: Inferred from physical interaction	16037816	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	12070131	RGD
enables signaling receptor binding	IPI IPI: Inferred from physical interaction	16037816	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in endosomal transport	IMP IMP: Inferred from mutant phenotype	18299352	RGD
involved in positive regulation of receptor recycling	IMP IMP: Inferred from mutant phenotype	12070131	RGD
involved in postsynaptic neurotransmitter receptor cycle	IMP IMP: Inferred from mutant phenotype	15911354	RGD
involved in regulation of long-term synaptic potentiation	IMP IMP: Inferred from mutant phenotype	15911354	RGD
involved in spontaneous synaptic transmission	IMP IMP: Inferred from mutant phenotype	15911354	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	28874679	RGD
located in early endosome	IDA IDA: Inferred from direct assay	28874679	RGD
located in early endosome membrane	IDA IDA: Inferred from direct assay	12070131	RGD
located in endosome	IDA IDA: Inferred from direct assay	18299352	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	12070131	RGD
located in late endosome	IDA IDA: Inferred from direct assay	28874679	RGD
located in lysosomal lumen	IDA IDA: Inferred from direct assay	28874679	RGD
is active in postsynaptic endosome	IDA IDA: Inferred from direct assay	12070131	RGD
located in recycling endosome membrane	IDA IDA: Inferred from direct assay	12070131	RGD
located in somatodendritic compartment	IDA IDA: Inferred from direct assay	12070131	RGD
located in trans-Golgi network membrane	IDA IDA: Inferred from direct assay	28874679	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

neuronal vesicle trafficking-associated protein 1

brain neuron cytoplasmic protein 1/2	brain specific mRNA b
neuron specific gene family member 1	neuron-enriched endosomal protein of 21 kDa
neuron-specific protein family member 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09593	NSG1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nsg1	NCBI	NCBI:27065

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