Rab38 - RAB38, member RAS oncogene family Gene

Rattus norvegicus

Also known as Ruby

Gene ID: 252916 | Gene type: protein coding

About Rab38

Summary

Enables GTP binding activity. Involved in platelet dense granule organization and positive regulation of phosphatidylcholine biosynthetic process. Located in cytosol and vesicle. Colocalizes with Golgi apparatus and endoplasmic reticulum. Used to study Hermansky-Pudlak syndrome; platelet storage pool deficiency; and proteinuria. Orthologous to human RAB38 (RAB38, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab38 Products(1)

mRNA	Protein	Name
NM_145774.3	NP_665717.1	ras-related protein Rab-38

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTP binding	IDA IDA: Inferred from direct assay	15843158	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in platelet dense granule organization	IMP IMP: Inferred from mutant phenotype	18983523	RGD
involved in positive regulation of melanin biosynthetic process	IMP IMP: Inferred from mutant phenotype	17043139	RGD
involved in positive regulation of phosphatidylcholine biosynthetic process	IDA IDA: Inferred from direct assay	28438206	RGD
involved in positive regulation of protein localization to cell periphery	IMP IMP: Inferred from mutant phenotype	17043139	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell body	IDA IDA: Inferred from direct assay	17043139	RGD
located in melanosome	IDA IDA: Inferred from direct assay	17043139	RGD
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	17043139	RGD
located in vesicle	IDA IDA: Inferred from direct assay	11337364	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ras-related protein Rab-38

Rab38, member of RAS oncogene family	red eyed dilution
ruby or red eyed dilution	small GTP binding protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11552	RAB38 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rab38	NCBI	NCBI:23682

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