Hsd17b1 - hydroxysteroid (17-beta) dehydrogenase 1 Gene

Also Known as 17BHD1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25322

Summary

Enables estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity. Involved in bone development; cellular response to metal ion; and steroid biosynthetic process. Located in cytosol. Orthologous to human HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b1 Products (1)

mRNA Protein Name
NM_012851.2 NP_036983.1 estradiol 17-beta-dehydrogenase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IDA
IDA: Inferred from direct assay
8612487 RGD
enables testosterone dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
8612487 RGD
Biological Process GO Annotation Evidence References Source
involved in bone development IEP
IEP: Inferred from expression pattern
15012600 RGD
involved in cellular response to metal ion IEP
IEP: Inferred from expression pattern
18602937 RGD
involved in estrogen biosynthetic process IDA
IDA: Inferred from direct assay
8612487 RGD
involved in testosterone biosynthetic process IDA
IDA: Inferred from direct assay
8612487 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

estradiol 17-beta-dehydrogenase 1

  • 17-beta-HSD 1

  • 17-beta-hydroxysteroid dehydrogenase type 1

  • Hydroxysteroid dehydrogenase 17 beta, type 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-159525 Linustedastatum Inhibitor 98.10% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-129583 Lepidiline A Activator 99.54% Unkown
HY-RS06389 HSD17B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19278 Hsd17b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25768 Hsd17b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd17b1 NCBI NCBI:3292