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Lepidiline A shows cytotoxic activity against HL-60 cells with an IC50 of 32.3 μM.

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Lepidiline A Chemical Structure

Lepidiline A Chemical Structure

CAS No. : 596093-98-0

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Description

Lepidiline A shows cytotoxic activity against HL-60 cells with an IC50 of 32.3 μM.

Molecular Weight

312.84

Formula

C19H21ClN2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=C(C)[N+](CC2=CC=CC=C2)=CN1CC3=CC=CC=C3.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (199.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1965 mL 15.9826 mL 31.9652 mL
5 mM 0.6393 mL 3.1965 mL 6.3930 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1965 mL 15.9826 mL 31.9652 mL 79.9131 mL
5 mM 0.6393 mL 3.1965 mL 6.3930 mL 15.9826 mL
10 mM 0.3197 mL 1.5983 mL 3.1965 mL 7.9913 mL
15 mM 0.2131 mL 1.0655 mL 2.1310 mL 5.3275 mL
20 mM 0.1598 mL 0.7991 mL 1.5983 mL 3.9957 mL
25 mM 0.1279 mL 0.6393 mL 1.2786 mL 3.1965 mL
30 mM 0.1066 mL 0.5328 mL 1.0655 mL 2.6638 mL
40 mM 0.0799 mL 0.3996 mL 0.7991 mL 1.9978 mL
50 mM 0.0639 mL 0.3197 mL 0.6393 mL 1.5983 mL
60 mM 0.0533 mL 0.2664 mL 0.5328 mL 1.3319 mL
80 mM 0.0400 mL 0.1998 mL 0.3996 mL 0.9989 mL
100 mM 0.0320 mL 0.1598 mL 0.3197 mL 0.7991 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lepidiline A596093-98-0OthersInhibitorinhibitorinhibit

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