Srgap3 - SLIT-ROBO Rho GTPase activating protein 3 Gene

Also Known as Gbi; WRP; MEGAP; Arhgap14; mKIAA0411; D130026O08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 259302

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of cell migration. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study schizophrenia. Orthologous to human SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Srgap3 Products (1)

mRNA Protein Name
NM_080448.4 NP_536696.4 SLIT-ROBO Rho GTPase-activating protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11672528 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
21325512 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
21325512 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21325512 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21325512 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLIT-ROBO Rho GTPase-activating protein 3

  • SLIT-ROBO Rho GTPase activating protein 2

  • WAVE-associated Rac GTPase-activating protein

  • brain stress early protein Gbi

  • rho GTPase-activating protein 14

  • srGAP2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13763 SRGAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13765 SRGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srgap3 NCBI NCBI:9901