FGF20 - fibroblast growth factor 20 Gene

Homo sapiens

Also known as RHDA2; FGF-20

Gene ID: 26281 | Gene type: protein coding

About FGF20

Cytogenetic location: 8p22 Genomic coordinates (GRCh38): 8:16,992,181-17,002,345 (from NCBI)

This gene has 2 transcripts (splice variants), 265 orthologues, 21 paralogues and is associated with 2 phenotypes. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a member of the Fibroblast Growth Factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009]

FGF20 Products(1)

mRNA	Protein	Name
NM_019851.3	NP_062825.1	fibroblast growth factor 20

FGF20 Protein Structure

FGF

0
100
211 a.a.

Protein Preferred Names

Protein Names

fibroblast growth factor 20

Recombinant FGF20 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700062AF	Animal-Free FGF-20 Protein, Human (His)	Q9NP95 (P3-T211)	≥95%

Related Diseases

Diseases

Alias

Renal Hypodysplasia/Aplasia 2

RHDA2

Hypodysplasia/Aplasia, Renal, Type 2

Renal Agenesis, Bilateral

Bilateral Renal Agenesis

Bilateral Renal Aplasia

Parkinson Disease, Late-Onset

Parkinson Disease	Parkinson'S Disease
PD	PARK
Parkinson Disease, Susceptibility To	Late Onset Parkinson'S Disease
Late Onset Parkinson Disease	Paralysis Agitans
Primary Parkinsonism	Idiopathic Parkinson Disease
Parkinson'S	Parkinson Disease, Late-Onset, Susceptibility To
Parkinson Disease, Age Of Onset, Modifier	Lewy Body Parkinson Disease
Idiopathic Parkinson'S Disease	Pd - [Parkinson Disease]
Parkinson Disease Nos	Parkinson, Nos
Primary Parkinson Disease

Potter'S Syndrome

Potter Sequence	Potter Syndrome
Oligohydramnios Sequence	Congenital Absence Of Kidneys Syndrome

Townes-Brocks Syndrome

Townes Syndrome	Renal-Ear-Anal-Radial Syndrome
Anus, Imperforate, With Hand, Foot And Ear Anomalies	Imperforate Anus-Hand, Foot And Ear Anomalies Syndrome
Rear Syndrome	Sensorineural Deafness With Imperforate Anus And Hypoplastic Thumbs
Tbs	Deafness, Sensorineural, With Imperforate Anus And Hypoplastic Thumbs
Imperforate Anus With Hand, Foot And Ear Anomalies	Anal-Ear-Renal-Radial Malformation Syndrome
Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome	Imperforate Anus-Hand And Foot Anomalies Syndrome
Sensorineural Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome	Sensorineural Hearing Loss With Imperforate Anus And Hypoplastic Thumbs

Renal Hypodysplasia/Aplasia 1

Renal Agenesis	Renal Adysplasia
Renal Aplasia	RHDA1
Hereditary Renal Aplasia	Hra
Hereditary Urogenital Adysplasia	Hypodysplasia/Aplasia, Renal, Type 1
Congenital Absence Of Kidneys Syndrome	Congenital Absence Of Kidney
Aplastic Kidney

Cakut

Renal Or Urinary Tract Malformation	Congenital Anomalies Of Kidney And Urinary Tract
Congenital Anomaly Of Kidney And Urinary Tract	Congenital Anomalies Of The Kidney And Urinary Tract
Kidney And Urinary Tract, Anomalies, Congenital	Renal Hypodysplasia, Nonsyndromic, 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04897	FGF20 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	FGF20	VGNC	VGNC:104454
Felis catus	FGF20	VGNC	VGNC:107333
Mus musculus	FGF20	MGD	MGI:1891346
Rattus norvegicus	FGF20	RGD	RGD:71068
Canis familiaris	FGF20	VGNC	VGNC:51802
Bos taurus	FGF20	VGNC	VGNC:28976
Others	FGF20	NCBI

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