Ttc26 - tetratricopeptide repeat domain 26 Gene

Also Known as hop; hpy; Ift56; 9330141E21Rik; 9430097H08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 264134

Summary

Enables intraciliary transport particle B binding activity. Involved in cilium organization; protein localization to cilium; and smoothened signaling pathway. Acts upstream of or within manchette assembly. Located in centrosome and ciliary basal body. Part of intraciliary transport particle B. Orthologous to human TTC26 (tetratricopeptide repeat domain 26). [provided by Alliance of Genome Resources, Apr 2022]

Ttc26 Products (1)

mRNA Protein Name
NM_153600.2 NP_705828.2 intraflagellar transport protein 56

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables intraciliary transport particle B binding IDA
IDA: Inferred from direct assay
19253336 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
25340710 MGI
Biological Process GO Annotation Evidence References Source
involved in axoneme assembly IMP
IMP: Inferred from mutant phenotype
28264835 MGI
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
22718903 MGI
involved in intraciliary transport IMP
IMP: Inferred from mutant phenotype
25340710 MGI
acts upstream of or within manchette assembly IMP
IMP: Inferred from mutant phenotype
9674995 MGI
involved in protein localization to cilium IMP
IMP: Inferred from mutant phenotype
28264835 MGI
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
25340710 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
7317942 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
19253336 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
22718903 MGI
located in cilium IDA
IDA: Inferred from direct assay
19253336 MGI
part of intraciliary transport particle B IDA
IDA: Inferred from direct assay
24596149 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
22718903 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intraflagellar transport protein 56

  • TPR repeat protein 26

  • hydrocephalic-polydactyl

  • protein hop-sterile

  • tetratricopeptide repeat protein 26

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15204 TTC26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttc26 NCBI NCBI:79989