CKAP2 - cytoskeleton associated protein 2 Gene

Homo sapiens

Also known as LB1; TMAP; se20-10

Gene ID: 26586 | Gene type: protein coding

About CKAP2

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:52,455,478-52,476,627 (from NCBI)

This gene has 7 transcripts (splice variants), 196 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 15.6), testis (RPKM 14.9) and 24 other tissues.

Summary

This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations. [provided by RefSeq, Nov 2013]

CKAP2 Products(4)

mRNA	Protein	Name
NM_001098525.3	NP_001091995.1	cytoskeleton-associated protein 2 isoform 2
NM_001286686.2	NP_001273615.1	cytoskeleton-associated protein 2 isoform 3
NM_001286687.2	NP_001273616.1	cytoskeleton-associated protein 2 isoform 4
NM_018204.5	NP_060674.3	cytoskeleton-associated protein 2 isoform 1

CKAP2 Protein Structure

CKAP2_C

0
200
400
600
683 a.a.

Protein Preferred Names

Protein Names

cytoskeleton-associated protein 2

CTCL tumor antigen se20-10

Related Diseases

Diseases

Alias

Enterocele

Vaginal Enterocele	Hernia
Hernias

Prolapse Of Female Genital Organ

Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant

ADLD	Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy
Leukodystrophy, Adult-Onset, Autosomal Dominant	Adult-Onset Autosomal Dominant Leukodystrophy
Autosomal Dominant Leukodystrophy With Autonomic Disease	Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy
Multiple Sclerosis-Like Disorder	Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly
Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease	Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type
Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms	Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy
Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset	Pelizaeus-Merzbacher Disease Autosomal Dominant
Pelizaeus-Merzbacher Disease Late-Onset Type	Adult Onset Autosomal Dominant Leukodystrophy

Filippi Syndrome

Scott Craniodigital Syndrome With Mental Retardation	Type 1 Syndactyly-Microcephaly-Intellectual Disability Syndrome
FLPIS	Scott Bryant Graham Syndrome
Craniodigital-Intellectual Disability Syndrome	Scott Craniodigital Syndrome
Scott-Bryant-Graham Syndrome	Syndactyly, Type I, With Microcephaly And Mental Retardation
Syndactyly Type I With Microcephaly And Intellectual Disability	Unusual Facial Appearance, Microcephaly, Growth And Intellectual Disability And Syndactyly
Craniodigital Syndrome With Intellectual Disability	Craniodigital Syndrome-Intellectual Disability Syndrome
Craniodigital Syndrome-Intellectual Disability, Scott Type	Intellectual Disability-Craniodigital Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02732	CKAP2 Human Pre-designed siRNA Set A		/	Unkown
HY-RS02733	CKAP2L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CKAP2	VGNC	VGNC:27380
Mus musculus	CKAP2	MGD	MGI:1931797
Macaca mulatta	CKAP2	VGNC	VGNC:71229
Rattus norvegicus	CKAP2	RGD	RGD:1311631
Canis familiaris	CKAP2	VGNC	VGNC:39286

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