Ss18 - SS18, nBAF chromatin remodeling complex subunit Gene

Also Known as Syt; Ssxt; D130059H17

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268996

Summary

Predicted to enable nuclear receptor coactivator activity. Acts upstream of or within several processes, including Ephrin Receptor signaling pathway; intracellular signal transduction; and neuronal stem cell population maintenance. Located in microtubule Cytoskeleton. Part of SWI/SNF complex and npBAF complex. Is expressed in ovary and primary sex cord. Human ortholog(s) of this gene implicated in synovial sarcoma. Orthologous to human SS18 (SS18 subunit of BAF chromatin remodeling complex). [provided by Alliance of Genome Resources, Apr 2022]

Ss18 Products (4)

mRNA Protein Name
NM_001161369.1 NP_001154841.1 protein SSXT isoform 2
NM_001161370.1 NP_001154842.1 protein SSXT isoform 3
NM_001161371.1 NP_001154843.1 protein SSXT isoform 4
NM_009280.2 NP_033306.2 protein SSXT isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell morphogenesis IDA
IDA: Inferred from direct assay
17686994 MGI
acts upstream of or within cell morphogenesis IGI
IGI: Inferred from genetic interaction
17686994 MGI
acts upstream of or within cytoskeleton organization IDA
IDA: Inferred from direct assay
17686994 MGI
acts upstream of or within ephrin receptor signaling pathway IDA
IDA: Inferred from direct assay
17686994 MGI
acts upstream of or within intracellular signal transduction IDA
IDA: Inferred from direct assay
17881493 MGI
acts upstream of or within microtubule cytoskeleton organization IDA
IDA: Inferred from direct assay
17686994 MGI
acts upstream of or within neuronal stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
23785148 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
17686994 MGI
Cellular Component GO Annotation Evidence References Source
part of SWI/SNF complex IDA
IDA: Inferred from direct assay
29374058 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
17686994 MGI
part of npBAF complex IDA
IDA: Inferred from direct assay
23785148 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein SSXT

  • synovial sarcoma associated SS18-beta

  • synovial sarcoma associated SS18-delta

  • synovial sarcoma associated SS18-gamma

  • synovial sarcoma translocation, Chromosome 18

  • synovial sarcoma, translocated to X chromosome

  • synovial sarcoma-associated Ss18-alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148739 dBRD 9-A 99.50% Unkown
HY-RS13802 SS18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13803 SS18L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19385 Ss18 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25877 Ss18 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ss18 NCBI NCBI:6760