Myo9a - myosin IXa Gene

Also Known as C230003M11; 4732465J09Rik; C130068I12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 270163

Summary

Predicted to enable several functions, including ATP binding activity; GTPase activator activity; and actin binding activity. Involved in regulation of neuron projection arborization. Located in axonal growth cone. Is expressed in several structures, including incisor enamel organ; limb; nervous system; sensory organ; and thyroid gland. Used to study focal segmental glomerulosclerosis and obstructive hydrocephalus. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (Myosin IXA). [provided by Alliance of Genome Resources, Apr 2022]

Myo9a Products (1)

mRNA Protein Name
NM_173018.2 NP_766606.2 unconventional myosin-IXa

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in postsynaptic specialization organization IDA
IDA: Inferred from direct assay
26834556 MGI
involved in postsynaptic specialization organization IEP
IEP: Inferred from expression pattern
26834556 MGI
involved in postsynaptic specialization organization IMP
IMP: Inferred from mutant phenotype
26834556 MGI
involved in regulation of neuron projection arborization IMP
IMP: Inferred from mutant phenotype
27259756 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
26834556 MGI
is active in Schaffer collateral - CA1 synapse IEP
IEP: Inferred from expression pattern
26834556 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
26834556 MGI
located in axonal growth cone IDA
IDA: Inferred from direct assay
27259756 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-IXa

  • unconventional myosin-9a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08952 MYO9A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo9a NCBI NCBI:4649