Cadps - Ca2+-dependent secretion activator Gene

Also Known as CAPS; CAPS1; mKIAA1121

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27062

Summary

Enables protein kinase binding activity. Involved in presynaptic dense core vesicle exocytosis and synaptic vesicle priming. Acts upstream of or within Catecholamine secretion and vesicle organization. Located in cytoplasmic vesicle. Is active in glutamatergic synapse. Is expressed in several structures, including adrenal gland; heart; nervous system; olfactory epithelium; and retina. Orthologous to human CADPS (calcium dependent secretion activator). [provided by Alliance of Genome Resources, Apr 2022]

Cadps Products (5)

mRNA Protein Name
NM_001042617.1 NP_001036082.1 calcium-dependent secretion activator 1 isoform 2
NM_001359919.1 NP_001346848.1 calcium-dependent secretion activator 1 isoform 3
NM_001359920.1 NP_001346849.1 calcium-dependent secretion activator 1 isoform 4
NM_001359921.1 NP_001346850.1 calcium-dependent secretion activator 1 isoform 5
NM_012061.3 NP_036191.2 calcium-dependent secretion activator 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12659812 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
21307259 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within catecholamine secretion IMP
IMP: Inferred from mutant phenotype
15820695 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
15820695 MGI
NOT acts upstream of or within exocytosis IMP
IMP: Inferred from mutant phenotype
15820695 MGI
involved in presynaptic dense core vesicle exocytosis IDA
IDA: Inferred from direct assay
25719439 MGI
involved in presynaptic dense core vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
25719439 MGI
involved in synaptic vesicle priming IDA
IDA: Inferred from direct assay
18022372 MGI
acts upstream of or within synaptic vesicle priming IGI
IGI: Inferred from genetic interaction
21040848 MGI
involved in synaptic vesicle priming IMP
IMP: Inferred from mutant phenotype
18022372 MGI
acts upstream of or within vesicle organization IMP
IMP: Inferred from mutant phenotype
15820695 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
15820695 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18022372 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18022372 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-dependent secretion activator 1

  • Ca2+-dependent activator protein for secretion

  • Cadependent activator protein for secretion

  • calcium-dependent activator protein for secretion 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01823 CADPS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01824 CADPS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cadps NCBI NCBI:8618