Cadps - Ca2+-dependent secretion activator Gene

Mus musculus

Also known as CAPS; CAPS1; mKIAA1121

Gene ID: 27062 | Gene type: protein coding

About Cadps

Summary

Enables protein kinase binding activity. Involved in presynaptic dense core vesicle exocytosis and synaptic vesicle priming. Acts upstream of or within Catecholamine secretion and vesicle organization. Located in cytoplasmic vesicle. Is active in glutamatergic synapse. Is expressed in several structures, including adrenal gland; heart; nervous system; olfactory epithelium; and retina. Orthologous to human CADPS (calcium dependent secretion activator). [provided by Alliance of Genome Resources, Apr 2022]

Cadps Products(5)

mRNA	Protein	Name
NM_001042617.1	NP_001036082.1	calcium-dependent secretion activator 1 isoform 2
NM_001359919.1	NP_001346848.1	calcium-dependent secretion activator 1 isoform 3
NM_001359920.1	NP_001346849.1	calcium-dependent secretion activator 1 isoform 4
NM_001359921.1	NP_001346850.1	calcium-dependent secretion activator 1 isoform 5
NM_012061.3	NP_036191.2	calcium-dependent secretion activator 1 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12659812	MGI
enables protein kinase binding	IPI IPI: Inferred from physical interaction	21307259	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within catecholamine secretion	IMP IMP: Inferred from mutant phenotype	15820695	MGI
acts upstream of or within establishment of localization in cell	IMP IMP: Inferred from mutant phenotype	15820695	MGI
NOT acts upstream of or within exocytosis	IMP IMP: Inferred from mutant phenotype	15820695	MGI
involved in presynaptic dense core vesicle exocytosis	IDA IDA: Inferred from direct assay	25719439	MGI
involved in presynaptic dense core vesicle exocytosis	IMP IMP: Inferred from mutant phenotype	25719439	MGI
involved in synaptic vesicle priming	IDA IDA: Inferred from direct assay	18022372	MGI
acts upstream of or within synaptic vesicle priming	IGI IGI: Inferred from genetic interaction	21040848	MGI
involved in synaptic vesicle priming	IMP IMP: Inferred from mutant phenotype	18022372	MGI
acts upstream of or within vesicle organization	IMP IMP: Inferred from mutant phenotype	15820695	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasmic vesicle	IDA IDA: Inferred from direct assay	15820695	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	18022372	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	18022372	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

calcium-dependent secretion activator 1

Ca2+-dependent activator protein for secretion	Cadependent activator protein for secretion
calcium-dependent activator protein for secretion 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01823	CADPS Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01824	CADPS2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cadps	NCBI	NCBI:8618

Name
Email *

	Sorry, but the email address you supplied was invalid.