Adamts16 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 271127

Summary

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]

Adamts16 Products (1)

mRNA Protein Name
NM_172053.3 NP_742050.2 A disintegrin and metalloproteinase with thrombospondin motifs 16 preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within branching involved in ureteric bud morphogenesis IMP
IMP: Inferred from mutant phenotype
23661704 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 16

  • a disintegrin-like and metallopetidase (reprolysin type) with thrombospondin type 1 motif, 16

  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16 preproprotein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00297 ADAMTS16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19099 Adamts16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25588 Adamts16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamts16 NCBI NCBI:170690